Common Name(s): Anti-collagenase-1 mouse monoclonal antibody,anti-collagenase-1 mouse monoclonal antibody,antibody-based mmp-1 inhibitor,precision anti-aging biologic
CAS Number: N/a
DESCRIPTION
What It Does: Specifically binds and neutralises mmp-1 collagenase preventing collagen degradation โ providing the highest specificity anti-collagenase protection available, without the off-target effects of broad-spectrum mmp inhibitors.
Why It's Used: Monoclonal antibody specificity for mmp-1 provides 1000ร selectivity versus broad-spectrum zinc-chelating mmp inhibitors โ the antibody's paratope geometry exactly complementing the mmp-1 epitope for high-affinity (kd ~1-10 nm) specific neutralisation.
How It Works: The monoclonal antibody binds mmp-1 at an allosteric or active-site epitope with kd ~1-10 nm โ the antibody-antigen complex prevents mmp-1 from accessing collagen substrate. unlike zinc chelators (which also inhibit mmp-2, -9, -13), the antibody provides complete mmp-1 selectivity from epitope complementarity.
Typically Found In: Precision anti-aging,premium biology
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.001%โ0.1%
SOURCING & ETHICS
Vegan Status: No - animal-derived
Halal Status: Conditional - halal slaughter certificate required (species declaration and slaughter method)
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier. [audit 2026-07-29 rev2: name declares rendered fat or animal tissue; halal status depends on species and slaughter, neither of which is in the record. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Murine monoclonal antibodies have potential immunogenicity on repeated skin application โ the potential for anti-murine igg antibody development after extended use should be assessed in long-term safety studies for leave-on cosmetic applications.
Last Verified: 2026-03-22
Primary Sources: Cosing database,anti-collagenase mmp-1 monoclonal antibody anti-aging review