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Common Name(s): Arthrospira extract,arthrospira (spirulina) extract,cyanobacteria phycocyanin,antioxidant immunomodulating marine active

CAS Number: N/a

DESCRIPTION

What It Does: Provides exceptional antioxidant protection from phycocyanin's open-chain tetrapyrrole radical scavenging (orac >85 ฮผmol te/mg), anti-inflammatory activity from phycocyanobilin's ho-1 upregulation, and skin conditioning from the gamma-linolenic acid and polysaccharide complex.

Why It's Used: Spirulina phycocyanin provides one of the highest antioxidant capacities per mass of any food or cosmetic ingredient โ€” the open-chain tetrapyrrole's extended conjugation providing exceptional radical scavenging with direct relevance to skin oxidative stress protection.

How It Works: Phycocyanin (c-phycocyanin, mw 120 kda) open-chain tetrapyrrole provides h-atom donation to ros (orac >85 ฮผmol te/mg vs vitamin c 4 ฮผmol te/mg โ€” >20ร— higher). phycocyanobilin inhibits nadph oxidase reducing oโ‚‚โ€ขโป generation; simultaneously upregulates ho-1 (heme oxygenase-1) anti-inflammatory enzyme. gamma-linolenic acid (omega-6, gla) competes with aa for cox/lox reducing pro-inflammatory prostaglandin production.

Typically Found In: Anti-aging,anti-inflammatory,marine beauty

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Spirulina extract stability: phycocyanin is ph-sensitive and light-unstable โ€” antioxidant-protected, light-opaque packaging and neutral ph formulation (6-7) maintains phycocyanin activity. the brilliant blue colour provides a natural cosmetic colourant function alongside the antioxidant benefit.

Last Verified: 2026-03-22

Primary Sources: Cosing database,arthrospira spirulina phycocyanin antioxidant anti-inflammatory review