Common Name(s): L-ascorbyl-6-palmitate,vitamin c palmitate,fat-soluble vitamin c

CAS Number: 137-66-6

DESCRIPTION

What It Does: Provides lipid-soluble antioxidant protection in skin and oil-based formulations.

Why It's Used: Oil-based formulations as fat-soluble vitamin c active and formulation antioxidant preservative (e304).

How It Works: Skin esterases cleave the bond releasing ascorbic acid and palmitic acid. lipophilic form may integrate into cell membranes for lipid-phase antioxidant protection.

Typically Found In: Oil serums,emulsions,sunscreens,anti-aging creams

TECHNICAL DETAILS

Primary Category: Active ingredient – vitamin c derivative

Secondary Functions: Lipid-soluble antioxidant,formulation preservative

Application Areas:

Typical Concentration Range: 0.1%–1%

SOURCING & ETHICS

Vegan Status: Conditional - feedstock declaration required

Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)

Source Notes: Esterification of ascorbic acid with palmitic acid. gras food additive (e304). [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – very low; palmitic acid minor concern

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Tocopherol,ferulic acid,niacinamide,spf

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Debate exists about efficiency of ester hydrolysis in intact skin and prooxidant potential of uv degradation products. formulating with the antioxidant triad (c+e+ferulic) mitigates this concern.

Last Verified: