Common Name(s): Centella asiatica glycoside,asiaticoside b
CAS Number: 16830-15-2
DESCRIPTION
What It Does: Accelerates wound healing and reduces scar formation through fibroblast activation and collagen synthesis stimulation.
Why It's Used: Clinically proven scar reduction and wound healing active โ the compound behind centella's legendary wound healing reputation.
How It Works: Promotes fibroblast proliferation and collagen synthesis via tgf-ฮฒ independent mechanism (distinct from madecassoside). also inhibits hyaluronidase protecting extracellular matrix. antimicrobial activity supports wound healing environment.
Typically Found In: Post-surgical products,scar treatments,wound healing formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ soothing / anti-inflammatory
Secondary Functions: Scar reduction,wound healing,collagen stimulation
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ2%
SOURCING & ETHICS
Vegan Status: Conditional - supplier confirmation required
Halal Status: Unverified - supplier confirmation required
Source Notes: Extracted from centella asiatica aerial parts alongside madecassoside, asiatic acid, and madecassic acid. [audit 2026-07-29 rev2: status downgraded on audit. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.
Safe for Sensitive Skin: Yes โ particularly recommended for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Asiaticoside's mechanism of wound healing involves release of aglycone asiatic acid after hydrolysis by skin beta-glucosidases. the glycoside form provides better stratum corneum penetration than the hydrophobic aglycone, acting as a prodrug for the active asiatic acid at the wound healing site.
Last Verified: