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Common Name(s): Benzyl hyaluronate,benzyl hyaluronate,benzyl hyaluronate,enhanced ha derivative

CAS Number: N/a

DESCRIPTION

What It Does: Provides 1000x water retention humectancy for superior hydration versus standard ha formulations.

Why It's Used: Benzyl modification provides performance advantages over standard sodium hyaluronate โ€” the modification providing the specific functional improvement for targeted applications

How It Works: Ha backbone (beta-1,3/beta-1,4 glucuronate-glcnac disaccharide repeat) provides the 1000x water binding from polyanionic carboxylate groups. benzyl modification alters the physicochemical properties โ€” molecular weight, charge, or lipophilicity โ€” to provide specific delivery or retention advantages versus unmodified ha.

Typically Found In: Anti-aging hydration,premium serums

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ humectant

Secondary Functions: Moisture retention,hydration

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“2%

SOURCING & ETHICS

Vegan Status: Conditional - feedstock declaration required

Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)

Source Notes: Plant-derived or fermentation-produced. [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for sensitive skin.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,barrier actives

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Ha molecular weight determines skin penetration vs surface hydration: ultra-low mw (<10 kda) penetrates sc to dermis; low mw (50-300 kda) intermediate penetration; high mw (>1 mda) surface film only. chemical modification (acetylation, crosslinking) provides independent control of these delivery properties.

Last Verified: 2026-03-22

Primary Sources: Cosing database,benzyl hyaluronate ha derivative review