Common Name(s): Bifida ferment lysate,postbiotic ferment,bioactive metabolite complex
CAS Number: N/a
DESCRIPTION
What It Does: Supports skin microbiome balance, delivers anti-inflammatory postbiotic metabolites, and provides biotransformed botanical actives with 10โ50ร improved sc penetration versus native glycoside forms.
Why It's Used: Preferred over live probiotic formats for conventional cosmetic stability and preservation compatibility, while delivering equivalent microbiome-supportive postbiotic metabolites.
How It Works: Multi-organism fermentation produces organic acids (acidifying skin surface ph to 4.5โ5.5), bacteriocins, and ฮฒ-glucosidases that deglycosylate botanical polyphenols to their more penetrant aglycone forms. tlr2-active cell wall fragments train skin immune cells toward anti-inflammatory tolerance.
Typically Found In: Microbiome skin care,anti-inflammatory
TECHNICAL DETAILS
Primary Category: Active ingredient โ skin microbiome support
Secondary Functions: Microbiome balance,prebiotic effect
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%โ15%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Fermentation-derived or plant-extracted.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; beneficial for sensitive skin.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,niacinamide,soothing actives
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Multi-organism postbiotic biotransformation selectively generates free aglycone polyphenols with 30โ50 da lower molecular weight and higher logp for significantly improved stratum corneum penetration.
Last Verified: 2026-03-12
Primary Sources: Cosing database,multi-organism ferment postbiotic review