Common Name(s): Calcium phosphoryl oligosaccharides,calcium phosphoryl oligosaccharides,oligosaccharide or polyol,prebiotic humectant active
CAS Number: N/a
DESCRIPTION
What It Does: Provides skin surface hydration from multiple hydroxyl group water binding and selectively nourishes beneficial microbiome organisms as a prebiotic substrate.
Why It's Used: Oligosaccharide prebiotics provide the dual benefit of humectancy and microbiome nutrition โ selectively fermented by lactobacillus and bifidobacterium skin commensals for enhanced microbiome-supportive skin care.
How It Works: Oligosaccharide prebiotic mechanism: selectively fermented by lactobacillus/bifidobacterium โ short-chain fatty acid production โ tight junction upregulation โ barrier reinforcement. not fermented by less beneficial microbiome organisms providing selective pressure for healthy microbiome composition.
Typically Found In: Moisturising,microbiome support
TECHNICAL DETAILS
Primary Category: Active ingredient โ humectant
Secondary Functions: Moisture retention,hydration
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived or fermentation-produced.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for sensitive skin.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,barrier actives
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Prebiotic oligosaccharide specificity is determined by the monosaccharide composition and linkage geometry โ beta-galactosides selectively nourish bifidobacterium; fructooligosaccharides nourish lactobacillus; the specific prebiotic selects for distinct beneficial species.
Last Verified: 2026-03-22
Primary Sources: Cosing database,calcium phosphoryl oligosaccharides oligosaccharide humectant prebiotic review