Common Name(s): Green tea extract,egcg,most published polyphenol

CAS Number: 84650-60-2

DESCRIPTION

What It Does: Provides egcg multi-mechanism anti-aging and maximum antioxidant.

Why It's Used: Most evidence-based cosmetic polyphenol — 1000+ published studies validate green tea's anti-oxidant, anti-photoaging, and anti-tumor activity making it the reference botanical antioxidant.

How It Works: Egcg: gallate ester provides maximum catechin antioxidant. mmp-1 inhibition: anti-photoaging collagen preservation. nf-kb + cox-2 inhibition: anti-inflammatory. vegf inhibition: anti-tumor. l-theanine: calming amino acid. very widely studied 1000+ papers.

Typically Found In: Anti-aging antioxidant serums — very widely used

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Egcg gallate ester multi-pathway binding: the galloyl group enables egcg to interact with multiple enzyme active sites (bcl-2, vegfr2, pi3k, akt) that ungallated catechins cannot bind, providing the 'promiscuous' multi-target activity that simultaneously activates apoptosis and blocks survival and angiogenesis signalling.

Last Verified: 2026-03-12

Primary Sources: Cosing database,egcg multi-study review