Common Name(s): L-carnitine,beta-hydroxy-gamma-trimethylaminobutyric acid
CAS Number: 541-15-1
DESCRIPTION
What It Does: Supports cellular energy production via fatty acid transport into mitochondria; regulates sebum fatty acid metabolism.
Why It's Used: Used in anti-aging and oily skin formulations for cellular energy support and sebum fatty acid regulation.
How It Works: Transfers long-chain acyl groups from cytosol to mitochondria via carnitine acyltransferase for beta-oxidation and atp production. in sebaceous glands, carnitine metabolism influences the fatty acid composition of sebum.
Typically Found In: Anti-aging serums,oily skin products,energy formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ fatty acid transport amino acid
Secondary Functions: Cellular energy,sebum regulation
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%โ3%
SOURCING & ETHICS
Vegan Status: Conditional - feedstock declaration required
Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)
Source Notes: Fermentation-derived or synthetic. natural skin component. [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; endogenous skin molecule.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. natural skin nmf component. ewg score: 1.
Works Well With: Hyaluronic acid,ceramides,peptides,other amino acids
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Carnitine-deficient conditions show marked sebaceous gland hyperactivity and altered sebum lipid profiles. this connection suggests topical carnitine may help normalize sebum composition in oily and acne-prone skin where sebaceous gland metabolic dysfunction contributes to comedone formation.
Last Verified: