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Common Name(s): Clary sage oil,muscatel sage

CAS Number: 8016-63-9

DESCRIPTION

What It Does: Provides herbaceous muscat fragrance with oestrogenic and anti-stress aromatherapy properties.

Why It's Used: Women's wellness fragrance โ€“ clary sage's phytoestrogenic activity and cortisol-reducing aromatherapy effects make it uniquely relevant for women's health-focused aromatic products.

How It Works: Linalyl acetate (60-70%) and linalool (12-20%) provide main fragrance character. sclareol (labdane diterpene) provides oestrogenic activity via er-beta binding. anxiolytic via linalool gaba-a activation.

Typically Found In: Women's fragrance,aromatherapy,hormonal balance products

TECHNICAL DETAILS

Primary Category: Fragrance โ€“ herbal essential oil

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%โ€“1%

SOURCING & ETHICS

Vegan Status: Conditional - supplier confirmation required

Halal Status: Unverified - supplier confirmation required

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier. [audit 2026-07-29 rev2: the record's own source_notes does not assert a non-animal origin, or instructs the reader to verify with the supplier; "yes" asserts knowledge the record does not hold. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Avoid high doses in pregnancy due to uterotonic activity. declared fragrance allergens: linalool, linalyl acetate. ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Clary sage's sclareol (labdane diterpene) provides oestrogenic activity by binding erฮฒ (oestrogen receptor beta) as a partial agonist. this phytoestrogen activity from a fragrance compound is notable because it provides potential hormonal skin benefit (collagen support, barrier function) alongside the primary fragrance effect โ€“ the same compound serving both purposes.

Last Verified: 2026-03-12

Primary Sources: Cosing database,ifra standards,serafino et al. sclareol oestrogenic study