Common Name(s): Colloidal/ionic silver,antimicrobial nanoparticle,broad-spectrum bactericidal

CAS Number: N/a

DESCRIPTION

What It Does: Provides broad-spectrum antimicrobial protection against bacteria, fungi, and viruses through silver ion release, with documented wound healing promotion through anti-biofilm activity and inflammatory modulation.

Why It's Used: Silver's multi-target antimicrobial mechanism prevents resistance development — bacteria cannot simultaneously mutate all silver-targeted enzymes (thiol enzymes, respiratory chain proteins, dna) to escape silver's activity, unlike single-target antibiotics.

How It Works: Ag⁺ ions bind bacterial thiol (-sh) groups in respiratory chain enzymes (nadh dehydrogenase, succinate dehydrogenase) inactivating atp synthesis. simultaneously, ag⁺ binds bacterial dna causing structural disruption, and binds cell wall lipopolysaccharide increasing membrane permeability. the three concurrent mechanisms provide resistance-proof bactericidal activity.

Typically Found In: Wound care,antimicrobial skin care

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Typical Concentration Range: Check concentration limits

SOURCING & ETHICS

Vegan Status: Conditional - supplier confirmation required

Halal Status: Unverified - supplier confirmation required

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier. [audit 2026-07-29 rev2: the record's own source_notes does not assert a non-animal origin, or instructs the reader to verify with the supplier; "yes" asserts knowledge the record does not hold. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Nano-silver regulatory status varies by market — eu considers nano-silver ingredients under nano-material notification requirements. ionic silver (ag⁺ salts) and colloidal forms have different regulatory pathways. formulators must verify nano-definition compliance for particle size specifications.

Last Verified: