Common Name(s): Corynebacterium ferment,corynebacterium ferment,corynebacterium postbiotic,skin commensal microbiome active
CAS Number: N/a
DESCRIPTION
What It Does: Provides skin microbiome-supportive activity from the healthy skin commensal corynebacterium's metabolite profile โ blis antimicrobials selectively targeting skin pathogens while supporting the commensal microbiome balance.
Why It's Used: Corynebacterium species constitute 20-30% of healthy armpit and skin microbiome โ their postbiotic metabolites represent the primary resident microbiome contribution to skin defence and homeostasis.
How It Works: Corynebacterium blis (bacteriocin-like inhibitory substances): lipid-embedded antimicrobial peptides that inhibit s. aureus and s. pyogenes through membrane disruption. cell wall mycolates (branched c32-c36 fatty acids): provide unique lipid conditioning from the bacterium's distinctive outer membrane lipid chemistry.
Typically Found In: Microbiome skin care,sensitive skin,underarm care
TECHNICAL DETAILS
Primary Category: Active ingredient โ skin microbiome support
Secondary Functions: Microbiome balance,prebiotic effect
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%โ10%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Fermentation-derived or plant-extracted.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; beneficial for sensitive skin.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,niacinamide,soothing actives
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Corynebacterium acnes and corynebacterium striatum have distinct metabolite profiles โ species-specific ferments should be characterised for their specific blis and mycolate profiles for targeted formulation.
Last Verified: 2026-03-22
Primary Sources: Cosing database,corynebacterium skin commensal postbiotic review