Common Name(s): Egg shell membrane extract,egg shell membrane extract,natural collagen/gag complex,wound healing joint-support active
CAS Number: N/a
DESCRIPTION
What It Does: Provides multiple ecm components simultaneously — native collagen peptides, gags (chondroitin, dermatan, hyaluronan), and lysozyme antibacterial activity — for comprehensive wound healing, anti-inflammatory, and skin conditioning from one natural matrix extract.
Why It's Used: Egg shell membrane provides the most economically accessible source of native ecm components — the membrane contains type i, v, and x collagen, dermatan sulfate, and ha in their native crosslinked matrix state, providing more physiologically relevant ecm conditioning than isolated individual components.
How It Works: Egg membrane hydrolysis releases: collagen type i/v peptides (fibroblast collagen synthesis receptor stimulation, gly-pro-hyp sequences); chondroitin sulfate/dermatan sulfate (heparan sulfate-mimetic growth factor presentation, anti-inflammatory); ha (1,000× water retention, cd44 receptor signalling); lysozyme (selective gram-positive antimicrobial through peptidoglycan hydrolysis).
Typically Found In: Anti-aging,wound care,skin conditioning
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–5%
SOURCING & ETHICS
Vegan Status: No - animal-derived
Halal Status: Conditional - dairy or egg origin statement required, plus rennet and enzyme origin upstream
Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: dairy or egg protein; rennet and enzyme origin upstream are undocumented. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Egg membrane allergen consideration: egg-derived ingredients may cause ige-mediated hypersensitivity in egg-allergic individuals — the inci name must be declared and egg allergen warning may be required in some markets.
Last Verified: 2026-03-22
Primary Sources: Cosing database,egg shell membrane extract ecm collagen gag review