Common Name(s): Hadsc conditioned media,adipose stem cell secretome,human fat stem cell cm extract
DESCRIPTION
What It Does: Delivers skin-renewing growth factors secreted by fat-derived stem cells for advanced anti-aging.
Why It's Used: Hadscs secrete over 100 growth factors (egf, fgf, vegf, tgf-ฮฒ, kgf) and cytokines into culture media; the conditioned media (secretome) contains this growth factor cocktail in a natural biological matrix.
How It Works: Egf (cell proliferation), fgf-2 (fibroblast activation), vegf (vascularization), tgf-ฮฒ1 (collagen stimulation), kgf (keratinocyte growth); combined natural growth factor signaling supports comprehensive skin renewal.
Typically Found In: Ultra-premium anti-aging serums,regenerative skin care,stem cell beauty
TECHNICAL DETAILS
Primary Category: Active ingredient โ stem cell
Secondary Functions: Anti-aging,collagen stimulation,skin renewal
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ5%
SOURCING & ETHICS
Vegan Status: No - human-derived
Halal Status: No - human-derived; majority prohibition (juz' al-adami) - panel confirmation required
Source Notes: Human-derived cell conditioned media; requires strict ethical sourcing, donor consent, and regulatory compliance. [audit 2026-07-29 rev2: name declares human tissue, fluid or cell culture. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Human-derived; requires extensive safety testing; regulatory status varies by market.
Safe for Sensitive Skin: Conditional
SAFETY & COMPATIBILITY
Safety Profile: Requires strict regulatory compliance and human-derived material testing. ewg score: varies by region.
Works Well With: Peptides,other growth factor extracts,antioxidants
Avoid Combining With: Strict quality control; no significant formulation incompatibilities
SCIENTIFIC NOTE
Hadsc-derived conditioned media (secretome) contains a naturally balanced combination of growth factors without the safety concerns of whole-cell transplantation; studied clinically for wound healing, hair regrowth, and skin rejuvenation.
Last Verified: 2026-03-28
Primary Sources: Cosing database,inci dictionary