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Common Name(s): Frescolat ml,menthyl lactic acid ester

CAS Number: 59259-38-0

DESCRIPTION

What It Does: Provides sustained, milder cooling sensation with lower irritation than free menthol for leave-on applications.

Why It's Used: Premium cooling agent for leave-on facial and body formulations where menthol's intensity and irritation are undesirable.

How It Works: Lactate ester of menthol provides slower hydrolysis by skin esterases releasing free menthol gradually. reduced initial trpm8 stimulus provides gentler, more sustained cooling vs free menthol's intense immediate burst. better skin tolerance for leave-on applications.

Typically Found In: Leave-on cooling products,after-sun serums,scalp cooling treatments

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ sustained cooling agent

Secondary Functions: Redness reduction,anti-inflammatory,calming

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“3%

SOURCING & ETHICS

Vegan Status: Conditional - feedstock declaration required

Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)

Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Yes โ€“ particularly recommended for sensitive skin

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

The ester prodrug strategy of menthyl lactate provides two advantages over free menthol: (1) slower release kinetics from enzymatic ester hydrolysis provides sustained cooling duration (2-3ร— longer than free menthol), and (2) reduced initial stimulus intensity reduces the sensory irritation that limits menthol in sensitive skin applications.

Last Verified: 2026-03-12

Primary Sources: Cosing database,symrise frescolat technical data