Common Name(s): Methylsilanol pca,methylsilanol pca,nmf-based functional active,bioactive pca complex

CAS Number: N/a

DESCRIPTION

What It Does: Provides pca humectant moisture retention from the nmf amino acid component alongside methylsilanol's specific cosmetic activity — one molecule delivering hydration and the methylsilanol-specific skin benefit simultaneously.

Why It's Used: Pca complexation extends the functional scope of both components — nmf pca provides the hydration carrier while the methylsilanol active provides targeted specific skin activity, from a single skin-compatible ingredient.

How It Works: Pca (pyrrolidone carboxylic acid, pka 3.6) exists as monoanion at ph 5.5 coordinating methylsilanol ions through the carboxylate and lactam carbonyl — controlled metal release from the pca complex in the sc provides bioavailable methylsilanol alongside the nmf humectant activity.

Typically Found In: Anti-aging,functional care,nmf restoration

TECHNICAL DETAILS

Primary Category: Active ingredient – humectant

Secondary Functions: Moisture retention,hydration

Application Areas:

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived or fermentation-produced.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for sensitive skin.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,barrier actives

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Copper pca provides zn-sod-like antioxidant activity from copper ion catalytic radical dismutation while the pca moiety simultaneously replenishes nmf — dual antioxidant and humectant from one ingredient.

Last Verified: 2026-03-22

Primary Sources: Cosing database,methylsilanol pca nmf pca complex review