Common Name(s): Niacinamide ascorbate,niacinamide ascorbate,niacinamide salt/conjugate,multi-function vitamin b3 derivative
CAS Number: N/a
DESCRIPTION
What It Does: Provides niacinamide brightening from melanin transfer synapse inhibition alongside the counterion's specific complementary skin benefit โ hydroxycitrate (anti-cellulite), salicylate (exfoliant), ascorbate (additional antioxidant brightening), mandelate (mild aha), or lactate (acid mantle).
Why It's Used: Niacinamide salts deliver niacinamide with enhanced formulation compatibility or dual-function activity from the counterion โ the ionic pair providing better solubility or penetration versus free niacinamide.
How It Works: Niacinamide ring at 3-5%: inhibits melanosome transfer from melanocyte to keratinocyte at the par-2 synapse โ reduced pigmentation. counterion provides additional activity: salicylate (bha keratolysis); ascorbate (tyrosinase inhibition); hydroxycitrate (atp-citrate lyase inhibition โ anti-lipogenic anti-cellulite); lactate (acid mantle reinforcement).
Typically Found In: Brightening,anti-aging,multi-function
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Niacinamide salt efficacy vs free niacinamide: salt forms typically provide equivalent niacinamide release with improved specific formulation properties โ the counterion compatibility and solubility advantages make salts preferable for targeted formulation types.
Last Verified: 2026-03-22
Primary Sources: Cosing database,niacinamide ascorbate niacinamide conjugate salt brightening review