Common Name(s): Oligopeptide-127 rh-oligopeptide-1
DESCRIPTION
What It Does: Rejuvenates skin by combining an anti-aging peptide with a recombinant human egf analog.
Why It's Used: Used where combined egf signaling and multi-pathway anti-aging activity is desired.
How It Works: Rh-oligopeptide-1 (rh-egf analog) activates egfr for cell proliferation; oligopeptide-127 provides complementary anti-aging activity.
Typically Found In: Premium anti-aging serums
TECHNICAL DETAILS
Primary Category: Active ingredient โ peptide
Secondary Functions: Anti-aging active,skin conditioning agent
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.001%โ0.1%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic and recombinant peptides.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Generally well tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile. ewg score: 1.
Works Well With: Other peptides,retinoids,vitamin c
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Rh-oligopeptide-1 (rh-egf) activates egfr on keratinocytes and fibroblasts supporting skin renewal and collagen synthesis.
Last Verified: 2026-03-28
Primary Sources: Cosing database,inci dictionary