Common Name(s): Oligopeptide-6,oligopeptide-6,anti-aging signal oligopeptide,skin conditioning active
CAS Number: N/a
DESCRIPTION
What It Does: Provides receptor-mediated anti-aging activity — stimulating collagen synthesis, inhibiting mmp degradation, or modulating specific skin receptor pathways at ppm concentrations.
Why It's Used: Oligopeptide sequences provide precise receptor pharmacology from defined molecular structures — mechanism-based efficacy claims from quantifiable receptor-ligand interactions.
How It Works: Oligopeptide sequence → receptor active site binding → intracellular signalling → col1a1/col3a1 upregulation + mmp inhibition. spps synthesis provides >98% purity for reproducible pharmacological response.
Typically Found In: Anti-aging serums,specialty actives
TECHNICAL DETAILS
Primary Category: Active ingredient – peptide
Secondary Functions: Collagen synthesis,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1–5000 ppm
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetically produced via solid-phase peptide synthesis (spps).
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating at recommended concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Retinoids,niacinamide,vitamin c,hyaluronic acid
Avoid Combining With: Strong acids below ph 3.5; oxidising agents
SCIENTIFIC NOTE
Oligopeptide inci numbering: each assigned number from the cosing registry designates a unique amino acid sequence — the numbered series enables targeting of different receptor subtypes across the full oligopeptide catalogue.
Last Verified: 2026-03-22
Primary Sources: Cosing database,oligopeptide-6 anti-aging review