Common Name(s): Oligopeptide-83,oligopeptide-83,anti-aging signal oligopeptide,skin conditioning active

CAS Number: N/a

DESCRIPTION

What It Does: Provides receptor-mediated anti-aging activity — stimulating collagen synthesis, inhibiting mmp degradation, or modulating specific skin receptor pathways at ppm concentrations.

Why It's Used: Oligopeptide sequences provide precise receptor pharmacology from defined molecular structures — mechanism-based efficacy claims from quantifiable receptor-ligand interactions.

How It Works: Oligopeptide sequence → receptor active site binding → intracellular signalling → col1a1/col3a1 upregulation + mmp inhibition. spps synthesis provides >98% purity for reproducible pharmacological response.

Typically Found In: Anti-aging serums,specialty actives

TECHNICAL DETAILS

Primary Category: Active ingredient – peptide

Secondary Functions: Collagen synthesis,anti-aging

Application Areas:

Typical Concentration Range: 1–5000 ppm

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetically produced via solid-phase peptide synthesis (spps).

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating at recommended concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Retinoids,niacinamide,vitamin c,hyaluronic acid

Avoid Combining With: Strong acids below ph 3.5; oxidising agents

SCIENTIFIC NOTE

Oligopeptide inci numbering: each assigned number from the cosing registry designates a unique amino acid sequence — the numbered series enables targeting of different receptor subtypes across the full oligopeptide catalogue.

Last Verified: 2026-03-22

Primary Sources: Cosing database,oligopeptide-83 anti-aging review