Common Name(s): Ethyl panthenol,lipophilic panthenol
CAS Number: 667-83-4
DESCRIPTION
What It Does: Deeply conditions hair and skin in anhydrous formulas; improves manageability and shine.
Why It's Used: Used in hair oils, waxes, and waterless formulas where panthenol's water solubility prevents incorporation.
How It Works: Ethyl ether modification increases lipophilicity (log p โ1.6 to ~0.4), improving penetration into lipid-rich hair cortex and stratum corneum.
Typically Found In: Hair oils,anhydrous conditioners,waterless products,beard oils
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin b5 lipophilic derivative
Secondary Functions: Deep hair penetration,moisturizing
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ3%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Increased lipophilicity allows deeper penetration into damaged, porous hair shafts vs panthenol, providing superior conditioning for chemically treated hair.
Last Verified: 2026-03-12
Primary Sources: Cosing database,cir safety assessment,basf technical data