Common Name(s): Papaya extract,papaw extract

CAS Number: 94349-61-8

DESCRIPTION

What It Does: Provides papain-based enzymatic exfoliation alongside natural vitamin c and carotenoid antioxidants.

Why It's Used: Tropical enzyme exfoliant with natural vitamin c, beta-carotene, and papain for combined brightening and enzymatic renewal.

How It Works: Papain provides keratin-specific enzymatic exfoliation (see papain entry). beta-carotene provides photoprotective antioxidant activity. vitamin c from fresh papaya provides brightening and collagen cofactor activity.

Typically Found In: Tropical enzyme peels,natural brightening masks

TECHNICAL DETAILS

Primary Category: Active ingredient – brightening / tyrosinase inhibitor

Secondary Functions: Melanin inhibition,hyperpigmentation reduction

Application Areas:

Typical Concentration Range: 1%–15%

SOURCING & ETHICS

Vegan Status: Yes – from carica papaya fruit

Halal Status: Yes

Source Notes: Synthetic or plant-derived.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. use with spf for maximum efficacy. ewg score: 1.

Works Well With: Niacinamide,vitamin c,alpha-arbutin,tranexamic acid,spf

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Fresh papaya fruit extract contains both functional papain enzyme and ~75mg/100g vitamin c – more than oranges. processing conditions determine whether both activities are preserved: high-heat processing destroys both, while aqueous cold extraction can retain both, making processing conditions critical for extract bioactivity.

Last Verified: 2026-03-12

Primary Sources: Cosing database,cir safety assessment