Common Name(s): Peg-222 pentaerythrityl adipate-succinimide dendrimer
DESCRIPTION
What It Does: Enables controlled delivery of cosmetic actives attached to its succinimide sites.
Why It's Used: Used as a scaffold to conjugate peptides or other amines for controlled cosmetic active delivery.
How It Works: Peg-222 provides water solubility; pentaerythrityl core provides 4 branching arms; adipate linkers provide flexibility; succinimide groups provide amine conjugation sites.
Typically Found In: Advanced active delivery cosmetics
TECHNICAL DETAILS
Primary Category: Specialty ingredient โ delivery system
Secondary Functions: Delivery system,film former
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ0.5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic peg dendrimer.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Generally well tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile. ewg score: 1โ2.
Works Well With: Peptides and amines being conjugated
Avoid Combining With: Verify compatibility with conjugated active
SCIENTIFIC NOTE
Peg dendrimers provide precisely controlled molecular architecture; the succinimide groups allow bioconjugation to peptides and vitamins under mild conditions.
Last Verified: 2026-03-28
Primary Sources: Cosing database,inci dictionary