Common Name(s): Perfluorocarbon,cโf bond oxygen carrier,skin oxygenation active
CAS Number: N/a
DESCRIPTION
What It Does: Dissolves and delivers molecular oxygen to skin surface through the perfluorocarbon's extraordinary oโ solubility, supporting mitochondrial energy metabolism in skin cells and accelerating wound healing through enhanced oxygen availability.
Why It's Used: Perfluorocarbons are the only cosmetic actives providing genuine molecular oxygen delivery to skin โ oโ solubility 20โ50ร higher than water enables meaningful oxygen flux to the skin surface from topically applied perfluorocarbon formulations.
How It Works: Cโf bond energy (116 kcal/mol, highest of any single bond) creates chemically inert surface with near-zero interaction energy. fluorine's electronegativity polarises cโf bonds to create a non-polar electron cloud โ the 'teflon-like' chemistry dissolves oโ by weak london dispersion forces at capacity 20โ50ร water. henry's law governs oโ release to skin: dissolved oโ concentration drives diffusion flux at the formulation-skin interface.
Typically Found In: Oxygenation skin care,wound healing
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ10%
SOURCING & ETHICS
Vegan Status: Conditional - supplier confirmation required
Halal Status: Unverified - supplier confirmation required
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier. [audit 2026-07-29 rev2: the record's own source_notes does not assert a non-animal origin, or instructs the reader to verify with the supplier; "yes" asserts knowledge the record does not hold. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Perfluorocarbon environmental persistence: some longer-chain pfcs are classified as persistent pollutants (pfas concerns). cosmetic-use pfcs like perfluorodecalin are shorter-chain variants with better environmental profiles than pfas โ formulators should verify current regulatory status in target markets.
Last Verified: 2026-03-12
Primary Sources: Cosing database,perfluorocarbon oโ delivery environmental review