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Common Name(s): Lecithin/phospholipid,cell membrane lipid,emulsifier barrier repair

CAS Number: N/a

DESCRIPTION

What It Does: Stabilises o/w and w/o emulsions through biomimetic phospholipid bilayer formation, supplements sc barrier lipids for barrier repair, and forms liposomes and lamellar delivery vehicles for encapsulated active delivery.

Why It's Used: Phospholipids are uniquely bifunctional: they provide conventional emulsification and form genuine liposomal bilayer vesicles for encapsulated active delivery โ€” a dual function unavailable from synthetic emulsifiers.

How It Works: The phosphocholine head group provides strong h-bonding hydrophilicity while the dual fatty acid tails provide lipophilic anchoring โ€” this wedge-shaped geometry spontaneously forms closed bilayer vesicles (liposomes) that encapsulate actives for sustained release and enhanced sc penetration.

Typically Found In: Emulsions,liposomal delivery,barrier repair

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ emollient

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“15%

SOURCING & ETHICS

Vegan Status: No - animal-derived

Halal Status: Conditional - animal origin stated in the record's own description; documentation required

Source Notes: Plant-derived, synthetic or animal-derived. verify source. [audit 2026-07-29 rev2: pass-1 miss: the record's own detail text states an animal derivation, but pass 1 classified on the name and source_notes only. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 1/5 โ€“ low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Phospholipid's wedge-shaped geometry (large head relative to two acyl tails) preferentially forms spherical bilayer vesicles (liposomes) rather than flat lamellar phases โ€” this curvature preference enables self-assembly of drug delivery liposomes simply by hydration of the phospholipid film.

Last Verified: 2026-03-12

Primary Sources: Cosing database,lecithin phospholipid liposomal delivery review