Common Name(s): Vitamin k1 pharmaceutical grade,phylloquinone usp

CAS Number: 84-80-0

DESCRIPTION

What It Does: Reduces bruising and dark circles in post-procedure and eye care applications at pharmaceutical purity.

Why It's Used: Pharmaceutical-grade vitamin k1 in higher-potency preparations for clinical skincare and post-procedure recovery.

How It Works: Identical mechanism to phylloquinone – activates vitamin k-dependent proteins through gamma-carboxylation of glutamic acid.

Typically Found In: Post-procedure skincare,eye creams,bruise healing,laser aftercare

TECHNICAL DETAILS

Primary Category: Active ingredient – vitamin k1 (pharmaceutical grade)

Secondary Functions: Dark circle reduction,bruise healing

Application Areas:

Typical Concentration Range: 0.1%–1%

SOURCING & ETHICS

Vegan Status: Conditional - supplier confirmation required

Halal Status: Unverified - supplier confirmation required

Source Notes: Pharmaceutical designation indicates usp/ep purity grade vs cosmetic-grade phylloquinone (same compound). [audit 2026-07-29 rev2: the record's own source_notes does not assert a non-animal origin, or instructs the reader to verify with the supplier; "yes" asserts knowledge the record does not hold. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating at cosmetic concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1. caution for patients on warfarin.

Works Well With: Retinol,caffeine,peptides,ceramides

Avoid Combining With: Warfarin anticoagulant therapy (consult physician)

SCIENTIFIC NOTE

The pharmaceutical designation 'phytonadione' indicates higher purity grade ensuring consistent potency for clinical applications. both phytonadione and phylloquinone are chemically identical – vitamin k1.

Last Verified: 2026-03-12

Primary Sources: Cosing database,usp monograph,cir safety assessment