Common Name(s): Plant sterols,beta-sitosterol complex,phytosterol mix
CAS Number: 83-46-5
DESCRIPTION
What It Does: Provides plant sterol barrier lipid analogue with anti-inflammatory and 5-alpha-reductase inhibiting activity.
Why It's Used: Comprehensive plant sterol complex providing barrier repair, anti-inflammatory, and anti-androgenic activity in a natural plant-derived mixture mimicking cholesterol's skin functions.
How It Works: Beta-sitosterol integrates into stratum corneum lipid bilayers as cholesterol structural analogue for barrier repair. inhibits 5-alpha-reductase type i and ii for dht reduction. anti-inflammatory via nf-kb inhibition. campesterol and stigmasterol provide complementary barrier and anti-inflammatory activities.
Typically Found In: Barrier repair creams,anti-acne products,anti-aging formulas
TECHNICAL DETAILS
Primary Category: Active ingredient โ plant sterol complex
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ3%
SOURCING & ETHICS
Vegan Status: Conditional - supplier confirmation required
Halal Status: Unverified - supplier confirmation required
Source Notes: Plant-derived, synthetic or animal-derived. verify source. [audit 2026-07-29 rev2: the record's own source_notes does not assert a non-animal origin, or instructs the reader to verify with the supplier; "yes" asserts knowledge the record does not hold. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 1/5 โ low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Phytosterols' multiple concurrent mechanisms (barrier repair + 5-ar inhibition + anti-inflammation) from a single ingredient class provides comprehensive acne-relevant benefits from natural plant cell membrane components. beta-sitosterol's structural identity to cholesterol (one ethyl group difference at c-24) allows barrier integration while the different c-24 substitution subtly alters enzyme binding, providing 5-ar inhibition not seen with mammalian cholesterol.
Last Verified: 2026-03-12
Primary Sources: Cosing database,bouic phytosterol review