Common Name(s): Poloxamine 604,tetronic 604,ethylenediamine eo/po block copolymer-604
DESCRIPTION
What It Does: Helps oil and water mix in formulas and can dissolve oily ingredients into water-based products.
Why It's Used: Grade 604 provides hlb ~5 for balanced to w/o applications.
How It Works: Ethylenediamine core with 4 peo/ppo block arms; hlb ~5 determined by peo/ppo ratio; temperature-sensitive gelation behavior.
Typically Found In: Pharmaceutical systems,clear formulations,o/w emulsions,specialty cleansers
TECHNICAL DETAILS
Primary Category: Functional ingredient โ emulsifier
Secondary Functions: Solubilizing,wetting,surfactant
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic; eo/po block copolymer; ethylenediamine core.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Considered very mild. well-established pharmaceutical safety profile.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile. ewg score: 1.
Works Well With: Anionic surfactants,nonionic surfactants,humectants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Grade 604 (tetronic 604): moderate mw; hlb ~5; balanced to w/o.
Last Verified: 2026-03-27
Primary Sources: Cosing database,inci dictionary,basf tetronic technical data