Common Name(s): Ellagitannin/gallate polyphenol,premium antioxidant,anti-melanogenic brightening
CAS Number: N/a
DESCRIPTION
What It Does: Provides among the most potent radical scavenging of any commercial botanical antioxidant, inhibits tyrosinase for brightening and hyperpigmentation treatment, chelates pro-oxidant feยฒโบ and cuยฒโบ, and provides anti-inflammatory nf-kb inhibition.
Why It's Used: Pyrogallol-type polyphenols (1,2,3-trihydroxybenzene) have the highest intrinsic radical-scavenging activity per phenol unit of any common antioxidant class โ three adjacent hydroxyl groups provide exceptionally stable radical delocalisation after electron donation.
How It Works: Three adjacent oh groups in the pyrogallol system provide concerted electron transfer to ros with radical stabilisation through extended aromatic delocalisation across the catechol-pyrogallol system. tyrosinase inhibition occurs through competitive cuยฒโบ chelation at the enzyme active site (chelation constant k_d ~0.1 ฮผm for gallic acid).
Typically Found In: Premium antioxidant serums,brightening,anti-aging
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.05%โ2%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Pomegranate pericarp contains 40โ50% ellagitannins by dry weight (punicalin, punicalagin) โ one of the highest tannin concentrations of any commercial plant material, providing extraordinary antioxidant extraction efficiency per gram of botanical material.
Last Verified: Cosing database,ellagic acid gallic acid pyrogallol antioxidant review
Primary Sources: 2026-03-12