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Common Name(s): Retinyl tallate,retinyl tallate,retinyl ester,tallow-esterified retinoid

CAS Number: N/a

DESCRIPTION

What It Does: Provides enzymatic hydrolysis-released retinol for rar receptor activation and retinaldehyde oxidation to retinoic acid in epidermis.

Why It's Used: Retinyl tallate delivers retinol activity via the ester hydrolysis pathway โ€” the tall oil fatty acid carrier providing an alternative lipophilic skin penetration matrix to the standard c16 palmitate ester.

How It Works: Retinyl ester โ†’ sc esterase hydrolysis โ†’ retinol โ†’ retinal dehydrogenase โ†’ all-trans-retinoic acid โ†’ rar-ฮฑ/ฮฒ/ฮณ nuclear receptor binding โ†’ retinoid response element gene activation.

Typically Found In: Anti-aging,sensitive skin retinoid

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%โ€“1%

SOURCING & ETHICS

Vegan Status: Conditional - feedstock declaration required

Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier. [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Retinyl esters provide significantly reduced irritancy versus retinol and retinoic acid โ€” the ester bond acting as a stability and controlled-release pro-drug mechanism.

Last Verified: 2026-03-22

Primary Sources: Cosing database,retinyl tallate retinyl ester review