Common Name(s): S-rna,s-rna,nucleic acid,cell communication molecule

CAS Number: N/a

DESCRIPTION

What It Does: Provides nucleoside and nucleobase delivery for adenosine receptor stimulation, nad+ precursor contribution, and cell energy metabolism support.

Why It's Used: S-rna is selected for nucleic acid-mediated cell communication — rna and dna fragments activate toll-like receptor signalling for skin immunity modulation and provide purine/pyrimidine bases as nad+ and energy cofactor precursors.

How It Works: Nucleic acid fragment → tlr3 activation (dsrna) or tlr9 activation (cpg dna) → interferon signalling or a2a adenosine receptor binding → collagen fibroblast stimulation.

Typically Found In: Anti-aging,cell communication

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Rna/dna cosmetic ingredients are hydrolysed to nucleosides/bases in formulation — the biologically active species are the purine/pyrimidine mononucleotides released by hydrolysis.

Last Verified: 2026-03-22

Primary Sources: Cosing database,s-rna nucleic acid skin active review