Common Name(s): Saccharomyces lysate extract,saccharomyces lysate extract,saccharomyces yeast ferment,brightening anti-aging postbiotic
CAS Number: N/a
DESCRIPTION
What It Does: Brightens skin through melanin transfer inhibition from yeast metabolites, activates sirt1 anti-aging longevity pathways from nad+ precursor delivery, provides antioxidant protection from ergothioneine, and modulates skin immunity from beta-glucan dectin-1 activation.
Why It's Used: Saccharomyces ferments are the heritage k-beauty brightening technology — the yeast metabolite profile simultaneously addressing brightening, anti-aging, and barrier-support through complementary mechanisms.
How It Works: Saccharomyces fermentation: nad+ precursors → sirt1 deacetylase activation → anti-aging gene expression; niacinamide-adjacent metabolites → melanin transfer synapse disruption → brightening; ergothioneine (trimethylbetaine thiourea) radical scavenging from resonance-stabilised thiyl radical; beta-1,3/1,6-glucan → dectin-1 → trained immunity.
Typically Found In: K-beauty brightening,anti-aging,premium postbiotic
TECHNICAL DETAILS
Primary Category: Active ingredient – skin microbiome support
Secondary Functions: Microbiome balance,prebiotic effect
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%–15%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Fermentation-derived or plant-extracted.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; beneficial for sensitive skin.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,niacinamide,soothing actives
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Substrate enriches the yeast metabolite base: grape lees provide resveratrol/anthocyanin biotransformation; rice provides kojic acid and rice amino acids; honey/royal jelly provide unique growth factor peptides alongside yeast metabolites — multi-substrate selection maximises bioactive diversity.
Last Verified: 2026-03-22
Primary Sources: Cosing database,saccharomyces yeast ferment brightening anti-aging review