Common Name(s): Sargachromanol c,sargachromanol c,marine chromanol,sargassum phlorotannin antioxidant

CAS Number: N/a

DESCRIPTION

What It Does: Provides hydroxyl radical scavenging from the phenolic chroman ring system and uvb photoprotection from the extended marine polyphenol conjugation in the sargassum-specific side chain.

Why It's Used: Sargachromanol c is selected for its unique marine chroman scaffold — sargachromanol combines tocopherol-related ring antioxidant chemistry with marine polyphenol conjugation, providing synergistic radical scavenging activity greater than either tocopherol or phlorotannin alone.

How It Works: Chroman ring: phenolic h-atom donation → radical quenching (koh >10⁸ m⁻¹s⁻¹); marine polyphenol chain: extended π-conjugation → additional radical delocalisation; combined: superior orac vs individual components.

Typically Found In: Marine antioxidant,anti-aging,photoprotection

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.01%–2%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Sargachromanol variants (a–f) differ in side-chain length and hydroxylation — variant f shows the highest tocopherol-equivalent radical scavenging activity.

Last Verified: 2026-03-22

Primary Sources: Cosing database,sargachromanol marine chromanol antioxidant review