Common Name(s): Thurfyl nicotinate,thurfyl nicotinate,nicotinic acid ester,vasodilating vitamin b3 active

CAS Number: N/a

DESCRIPTION

What It Does: Provides nicotinic acid-mediated prostaglandin d2 release for localised vasodilation, improving microcirculation and active delivery in scalp and skin applications.

Why It's Used: Thurfyl nicotinate is selected for the nicotinate ester vasodilatory mechanism — the prostaglandin-mediated flush response increases local microcirculation, enhancing active ingredient delivery and scalp blood flow for hair growth support.

How It Works: Nicotinate ester → skin esterase hydrolysis → nicotinic acid → prostaglandin d2 (pgd2) synthesis → cutaneous vasodilation → localised hyperaemia + active penetration enhancement.

Typically Found In: Scalp care,anti-hair loss,circulation

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

The flushing sensation from nicotinate esters is a predictable prostaglandin response — concentration titration controls intensity for consumer acceptability.

Last Verified: 2026-03-22

Primary Sources: Cosing database,thurfyl nicotinate nicotinate vasodilator review