Common Name(s): Decorinyl,pal-phe-arg-cit
CAS Number: N/a
DESCRIPTION
What It Does: Regulates collagen fiber diameter for improved collagen architecture, better skin texture, and reduced roughness.
Why It's Used: Unique anti-aging approach targeting collagen fiber organization rather than collagen synthesis quantity – addressing the quality and organization of existing collagen for improved texture.
How It Works: Decorin is the proteoglycan responsible for regulating collagen fibril diameter during ecm assembly. tripeptide-10 citrulline competes with decorin binding sites, modulating collagen fiber thickness toward youthful, smaller, more evenly organized fibrils.
Typically Found In: Premium anti-aging serums,skin texture products,collagen organizing formulations
TECHNICAL DETAILS
Primary Category: Active ingredient – decorin peptide / ecm organizer
Secondary Functions: Collagen organization,texture refinement,ecm architecture
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 100–1000 ppm
SOURCING & ETHICS
Vegan Status: Conditional - supplier confirmation required
Halal Status: Unverified - supplier confirmation required
Source Notes: Spps synthesis with citrulline modification. commercially available as decorinyl (lipotec). [audit 2026-07-29 rev2: the record's own source_notes does not assert a non-animal origin, or instructs the reader to verify with the supplier; "yes" asserts knowledge the record does not hold. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Exceptional safety profile. ewg score: 1.
Works Well With: Hyaluronic acid,ceramides,retinol,vitamin c,niacinamide
Avoid Combining With: Avoid mixing with high-concentration ahas at same ph (may hydrolyze peptide bonds)
SCIENTIFIC NOTE
Age-related collagen disorganization (thicker, irregular fibers vs thinner, organized youthful collagen) contributes to roughness and loss of skin clarity. tripeptide-10 citrulline addresses this organizational aspect of collagen aging that most peptides and retinoids cannot target.
Last Verified: 2026-03-12
Primary Sources: Cosing database,lipotec decorinyl technical data