Common Name(s): Uracil,uracil,nucleobase,skin cell dna/rna repair support

CAS Number: N/a

DESCRIPTION

What It Does: Provides uracil nucleobase substrate for skin cell dna repair, rna synthesis, or purine catabolism regulation depending on the specific nucleobase pharmacology.

Why It's Used: Uracil is selected for its nucleobase-mediated cell metabolism support — providing the specific pyrimidine or purine substrate that activates dna repair, rna synthesis, or energy metabolism pathways relevant to anti-aging and cellular maintenance.

How It Works: Uracil: nucleobase salvage pathway → nucleotide synthesis → dna/rna synthesis; cell cycle support → keratinocyte turnover normalisation; purine/pyrimidine substrate delivery.

Typically Found In: Anti-aging,cell repair

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.05%–3%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Uracil is absorbed via nucleobase transporters in keratinocytes — the salvage pathway provides an energy-efficient route to nucleotide synthesis bypassing de novo biosynthesis.

Last Verified: 2026-03-22

Primary Sources: Cosing database,uracil nucleobase cell metabolism review