Common Name(s): Viper venom,viper venom,waglerin synthetic analog,botox-like peptide source
CAS Number: N/a
DESCRIPTION
What It Does: Provides synthetic waglerin peptide postsynaptic acetylcholine receptor (nachr) competitive inhibition for temporary reduction of muscle-contraction wrinkle depth.
Why It's Used: Viper venom-derived peptide actives are selected for their topically applicable neuromuscular junction inhibition — the waglerin-like mechanism provides botulinum toxin-comparable wrinkle smoothing through acetylcholine receptor competition without the systemic risk of injectable toxin.
How It Works: Waglerin peptide analog: nachr competitive inhibition → reduced postsynaptic depolarisation → reduced muscle contraction → decreased dynamic wrinkle expression over 4–8 weeks of consistent application.
Typically Found In: Anti-aging,expression line treatment
TECHNICAL DETAILS
Primary Category: Active ingredient – peptide
Secondary Functions: Collagen synthesis,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.001%–1%
SOURCING & ETHICS
Vegan Status: No - animal-derived
Halal Status: Conditional - species, slaughter status, and synthetic-versus-animal confirmation required
Source Notes: Synthetically produced via solid-phase peptide synthesis (spps). [audit 2026-07-29 rev2: animal origin; may also be a synthetic bearing a legacy animal name. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating at recommended concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Retinoids,niacinamide,vitamin c,hyaluronic acid
Avoid Combining With: Strong acids below ph 3.5; oxidising agents
SCIENTIFIC NOTE
Cosmetic viper venom actives are 100% synthetic peptide analogs of the waglerin sequence — no actual venom extraction is involved in modern cosmetic formulations.
Last Verified: 2026-03-22
Primary Sources: Cosing database,viper venom waglerin peptide anti-aging review