
Highlights
WHAT IS IT?
Face oil with one ingredient
FEATURES
Instantly hydrates and locks in essential moisture, Helps boost the absorption of other active ingredients, Promotes microbiome diversity for healthier-looking skin
BEST FOR
All skin types
CHECKS
Paraben-free, sulfate-free
Who Is It For?
Adults Women And MenWhat Does It Help With?
Hydration Skin Barrier SupportBudget
Mid-rangeHow To Use
Which routine should it be used in?
Instructions:
Key Information
What Biossance Says
Product Description:
Squalane is the powerhouse ingredient at the heart of every Biossance formula. It's bioidentical to the moisture found in human skin, making it weightless and instantly absorbed and perfect for use all over the body. Our squalane is derived from sustainable sugarcane, a purer, vegan, more ethical, and more effective version than other forms of squalane. And since it replaces the need for similar moisture taken from the livers of sharks, it saves millions of these critical apex predators per year.
About the Brand:
Ingredients Overview
Ingredients List
Squalane
Key Ingredients
Squalane
Ingredients Details
Squalane
Common Name(s): Perhydrosqualene,2,6,10,15,19,23-hexamethyltetracosane
CAS Number: 0111-01-03
DESCRIPTION
What It Does: Provides endogenous-skin-identical emolliency with exceptional stability and skin compatibility.
Why It's Used: The most skin-compatible emollient โ chemically identical to human sebum squalene component with outstanding tolerability across all skin types.
How It Works: Fully saturated hydrocarbon with zero oxidation sites provides exceptional stability unlike squalene's 6 double bonds. integrates into stratum corneum lipid bilayers with near-perfect biocompatibility. provides antioxidant protection to formulation via radical quenching.
Typically Found In: Facial oils,serums,non-comedogenic moisturizers,luxury body care
TECHNICAL DETAILS
Primary Category: Functional ingredient โ emollient
Secondary Functions: Maximum biocompatibility,antioxidant stabilizer,non-comedogenic
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ100%
SOURCING & ETHICS
Vegan Status: Conditional โ plant-derived (sugarcane, olive) preferred; shark liver-derived being phased out
Halal Status: Yes โ plant-derived
Source Notes: Sustainable plant-derived squalane from sugarcane fermentation (amyris) or olive oil fractionation is preferred over shark liver-derived. chemically identical regardless of source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Squalene constitutes approximately 12-15% of human sebum โ the highest proportion of any skin lipid. topical squalane (stable, hydrogenated form) replenishes this abundant endogenous skin lipid. the complete absence of oxidizable double bonds (unlike squalene's 6 double bonds) eliminates the pro-oxidant concerns of natural squalene oxidation.
Last Verified: Cosing database,huang et al. squalane review,cir safety assessment
Primary Sources: 2026-03-12