
Highlights
WHAT IS IT?
Broad Spectrum Sunscreen with 10 ingredients described
FEATURES
Intense hydration, Repair of sun-damaged tissue, Reduces inflammation, Enhances hydration, Improves elasticity, Reduces dryness, Promotes healing, Neutralizes free radicals, Regulates melanin production, Lightens pigmentation, Anti-inflammatory, Antioxidant protection
BEST FOR
sensitive
CHECKS
Who Is It For?
What Does It Help With?
Sun Protection Pigmentation Control Hydration Skin HealingBudget
Premium ($76-$150)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Nykaa E retail limited Says
Product Description:
Explore the entire range of Face Sunscreen available on Nykaa. Shop more ALBIZZIA products here.You can browse through the complete world of ALBIZZIA Face Sunscreen.
About the Brand:
Ingredients Overview
Ingredients List
Sodium-Hyaluronate,Darutoside,Hydrolyzed-Wheat-Protein,Pro-Vitamin-B5-(Panthenol),3-O-Ethyl-Ascorbic-Acid,Albizia-Julibrissin-Bark-Extract,Glycyrrhiza-Glabra-(Licorice)-Root-Extract,Tocopheryl-Acetate-(Vitamin-E),Chamomile-Flower-Extract,Cyanocobalamin-(Vitamin-B12)
Key Ingredients
Sodium Hyaluronate,Darutoside,Hydrolyzed Wheat Protein,Pro-Vitamin B5 (Panthenol),3-O Ethyl Ascorbic Acid,Albizia Julibrissin Bark Extract,Glycyrrhiza Glabra (Licorice) Root Extract,Tocopheryl Acetate (Vitamin E),Chamomile Flower Extract,Cyanocobalamin (Vitamin B12)
Ingredients Details
Darutoside
Common Name(s): Darutoside,darutoside,siegesbeckia diterpene glycoside,anti-inflammatory joint-mimetic active
CAS Number: N/a
DESCRIPTION
What It Does: Provides dual nf-kb and cox-2 inhibition for comprehensive anti-inflammatory skin and scalp care โ the labdane diterpene's multiple inflammatory pathway targeting providing superior anti-inflammatory coverage from one natural compound.
Why It's Used: Darutoside's dual nf-kb + cox-2 inhibition provides complementary anti-inflammatory coverage โ nf-kb blocks cytokine gene transcription (upstream) while cox-2 inhibition blocks prostaglandin synthesis (downstream), providing more complete inflammatory cascade blockade than single-pathway inhibitors.
How It Works: Darutoside diterpene skeleton: iฮบb kinase ฮฒ inhibition via terpenoid binding โ nf-ฮบb nuclear translocation blocked โ reduced tnf-ฮฑ/il-1ฮฒ/il-6 (upstream pathway). simultaneously: cox-2 active site competitive inhibition โ reduced pge2/pgi2 โ reduced vasodilation and sensitisation (downstream pathway).
Typically Found In: Anti-inflammatory,scalp care,sensitive skin
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ1%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Siegesbeckia orientalis (st. paul's wort) has documented traditional use in tcm for rheumatoid arthritis โ the anti-inflammatory mechanism directly applicable to skin inflammatory conditions including eczema, scalp inflammation, and reactive skin.
Last Verified: Cosing database,darutoside labdane diterpene nf-kb cox-2 anti-inflammatory review
Primary Sources: 2026-03-22