Bioderma Cleanser - Sebium Gel Moussant - Acne Defence Cleanser For Oily Acne Prone Skin

DESCRIPTION

What It Does: Provides rapid-acting prebiotic microbiome support with humectant conditioning from short-chain fructan oligomers.

Why It's Used: Fast-acting prebiotic for rapid microbiome support — fos's shorter chain length provides faster fermentation by beneficial bacteria vs long-chain inulin, enabling quicker microbiome compositional shifts.

How It Works: Dp 2-10 fructooligomers (vs inulin's dp 10-60) provide more rapid access to bacterial fermentation enzymes. higher water solubility and humectant activity than long-chain inulin. more bioavailable to skin surface bacteria vs longer-chain inulin that penetrates deeper before fermentation.

Typically Found In: Prebiotic skin care,rapid microbiome support products

TECHNICAL DETAILS

Primary Category: Active ingredient – short-chain prebiotic

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–5%

SOURCING & ETHICS

Vegan Status: Yes – from sucrose enzymatic synthesis or inulin hydrolysis

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Fos's shorter chain length provides different prebiotic kinetics vs long-chain inulin: short-chain fos (dp 2-5) is fermented within 12-24 hours by surface bacteria, while long-chain inulin (dp 10-60) ferments over 48-72 hours. this temporal difference enables formulation of 'fast-acting' (fos) vs 'sustained-release' (inulin) prebiotic products with different microbiome support kinetics.

Last Verified: Cosing database,roberfroid fos prebiotic review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Laureth-2 contributes its primary cosmetic function to formulations — improving skin feel, stability, performance, or delivering a specific active benefit depending on its chemical class and concentration level.

Why It's Used: Formulators choose laureth-2 for its established efficacy in contributing the required functional property to their formulation — whether rheological control, active delivery, aesthetic enhancement, or preservation — supported by the cosmetic chemistry literature and regulatory assessment framework.

How It Works: Laureth-2 works through the characteristic mechanism of its chemical class — either through physicochemical interaction with the formulation matrix (surface activity, film formation, viscosity building) or through biological interaction with skin tissues (receptor binding, enzymatic substrate, barrier component integration). the specific mechanism follows from its molecular structure as detailed in peer-reviewed cosmetic chemistry literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Laureth-2 has been assessed within the regulatory framework applicable to cosmetic ingredients. at standard cosmetic use concentrations, the ingredient delivers documented functional benefit with an established safety profile based on the available toxicological and clinical evidence reviewed by regulatory bodies including cosing (eu), inci, and cir.

Last Verified: Cosing database,laureth-2 technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides exceptional hydroxyl radical scavenging antioxidant protection alongside humectant moisture retention.

Why It's Used: Used for potent hydroxyl radical scavenging where standard antioxidants (tocopherol, ascorbic acid) are less effective, combined with humectant activity.

How It Works: 6 hydroxyl groups provide both water binding (humectant) and direct hydroxyl radical (.oh) scavenging. hydroxyl radicals are the most reactive and damaging free radicals – mannitol is one of few compounds that scavenges them directly.

Typically Found In: Antioxidant formulations,premium moisturizers,protective skincare

TECHNICAL DETAILS

Primary Category: Functional ingredient – sugar alcohol / free radical scavenger

Secondary Functions: Free radical scavenger,superior antioxidant

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – plant-derived or synthetic

Halal Status: Yes

Source Notes: Plant-derived from ash tree manna, seaweed, mushrooms, or produced by reduction of mannose. gras food-approved.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Mannitol's rate constant for hydroxyl radical scavenging (k = 1.4 × 10^7 m^-1s^-1) makes it one of the most effective biological hydroxyl radical scavengers. this is important because hydroxyl radicals cannot be scavenged by standard antioxidants like tocopherol or ascorbic acid.

Last Verified: Cosing database,halliwell et al. free radical scavenging,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides humectant and solvent functionality with improved skin feel vs butylene glycol.

Why It's Used: Premium humectant solvent with superior skin feel to conventional diols for elegant premium formulation textures.

How It Works: Branched c4 structure provides good humectant activity. branching reduces viscosity and stickiness vs linear propylene glycol. excellent solvent for challenging actives. antimicrobial boosting from diol structure.

Typically Found In: Premium serums,active delivery systems

TECHNICAL DETAILS

Primary Category: Functional ingredient – humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Methylpropanediol's methyl branch provides a 25% reduction in dynamic viscosity vs linear butylene glycol at equivalent concentration — a physically measurable skin feel improvement from the branching's reduction of intermolecular attractive forces. this viscosity reduction translates directly to the 'less sticky, lighter' skin feel that premium formulations require.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function — skin conditioning, antioxidant protection, active biological benefit, or formulation function — at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Rhamnose has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,rhamnose technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides anticaries activity by starving cariogenic bacteria alongside humectant moisture retention.

Why It's Used: The anticaries sweetener — xylitol's non-fermentability by s. mutans prevents acid production from sugar metabolism for comprehensive caries prevention.

How It Works: S. mutans transports xylitol into cell via glucose transporter. xylitol-5-phosphate cannot be metabolised and accumulates intracellularly poisoning s. mutans. non-fermentability prevents acid production. stimulates saliva flow for natural remineralisation.

Typically Found In: Toothpaste,mouthwash,sugar-free gum,oral care

TECHNICAL DETAILS

Primary Category: Active ingredient – dental anticaries sugar alcohol

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 5%–30%

SOURCING & ETHICS

Vegan Status: Yes – from birch or corn cob

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Highly toxic to dogs — xylitol causes hypoglycemia. safe for humans at typical doses.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Xylitol's toxicity to s. mutans is bacterium-selective: the same glucose transporter that brings glucose into s. mutans also transports xylitol, but the phosphorylated product (xylitol-5-phosphate) cannot be metabolised and accumulates to toxic concentrations in s. mutans but not in human cells, which metabolise xylitol via a pentose phosphate pathway.

Last Verified: Cosing database,mäkinen xylitol caries review

Primary Sources: 2026-03-12