
California Naturals
California Naturals Re:GRO Anti-Thinning Scalp Serum
A clean, no-side-effects hair and scalp serum formulated with 5% Capixyl, rosemary, caffeine, and saw palmetto to promote stronger, fuller, and healthier hair with reduced breakage.
Paraben-free
Sulfate-free
Silicone-free
Fragrance-free
Color-safe
Thinning
Optimized for Your Environment & Lifestyle
Your Biodata Compatibility Analysis
Based on your 6 hair health indices and environmental factors
Poor Match
Significant incompatibilities
Growth Cycle Health Index
Hair Match
Hair Health Index Alignment
Optimal for OSI, SSI, DI, HSI
Ingredient Efficacy
Matching Ingredient Score
Environment Compatibility
Current UV, Air Quality & Humidity
Why This Works for Your Specific Profile
Damage Index:
Damage levels outside specified range may not benefit optimally from product formulation
Water Quality:
Fine hair becomes weighed down and greasy from heavy formulation
Hair:
No porosity-specific conflicts
Active Lifestyle:
High activity and frequent washing rapidly strip product benefits requiring excessive reapplication
Your Hair Profile Integration
Your Hair Archetype
Density Level
Washing Frequency
Shedding Level
Oil Level
Your Hair Health Indices
Oil Secretion (OSI)
Very low oil production
Scalp Sensitivity (SSI)
Very low sensitivity
Growth Rate (CMR)
Poor metabolism rate
Damage Index (DI)
Minimal damage
Hair Strength (HSI)
Very weak strength
Softness Index (SI)
Significant improvement needed
Water & Environmental Integration
Water:
Expected Results & Timeline
Key Highlights
What is it?
Scalp Serum with 5% Capixyl
Who Is It For
Adults
Budget
Rs. 1,942.36 - Rs. 3,884.72
Timeline
Use at least 4 times per week for 12 weeks for best results.
Why Youโll Love It
What Does It Help With?
Improving hair fullness, Reducing shedding and thinning, Strengthening hair from root to tip
Best for
Thinning hair and hair loss concerns
Features
Naturally derived ingredients, Fragrance-free, Free from Parabens, Sulfates, Silicones, and Phthalates, Safe for color-treated hair
Checks
Clean Ingredients, Cruelty-Free, Vegan, Sustainable Packaging, Give Back
Ingredients Overview
Ingredients List
aqua-water-eau, capixyl, aloe-barbadensis-leaf-juice, panthenol-vitamin-b5, 1-2-hexanediol-and-caprylyl-glycol, biotin, caffeine, rosmarinus-officinalis-rosemary-leaf-oil, adenosine, phytocelltec-solar-vitis, caffeine, cucurbita-pepo-pumpkin-seed-oil, serenoa-serrulata-fruit-extract, malus-domestica-fruit-cell-culture-extract-and-xanthan-gum-and-sodium-benzoate-and-aqua-water, ricinus-communis-castor-seed-oil, silica, ethylhexylglycerin, caprylyl-capryl-glucoside-60-active, carbomer
Key Ingredients
5%-capixyl, caffeine, biotin, rosmarinus-officinalis-rosemary-leaf-oil, cucurbita-pepo-pumpkin-seed-oil, serenoa-serrulata-fruit-extract, ricinus-communis-castor-seed-oil, silica
Ingredients Details
Adenosine
Common Name(s): Adenine riboside,9-beta-d-ribofuranosyladenine
CAS Number: 58-61-7
DESCRIPTION
What It Does: Reduces fine lines, stimulates collagen, firms skin, and reduces inflammation.
Why It's Used: Fda-recognized anti-wrinkle active with multi-action collagen stimulation + wrinkle reduction + anti-inflammatory efficacy.
How It Works: Activates adenosine a2a receptors on fibroblasts stimulating collagen type i. also activates pka pathway promoting atp production and reducing inflammatory cytokines.
Typically Found In: Anti-aging serums,wrinkle treatments,korean skincare
TECHNICAL DETAILS
Primary Category: Active ingredient โ purine nucleoside / anti-aging
Secondary Functions: Collagen stimulation,anti-inflammatory,cell energy
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.04%โ0.1%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. fda-recognized as safe and effective anti-wrinkle ingredient. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
A 2002 clinical study demonstrated 0.04% adenosine cream significantly reduced wrinkle depth and increased skin elasticity after 4 weeks. fda recognition requires controlled clinical trial evidence.
Last Verified: Cosing database,adenosine anti-aging clinical data,fda otc anti-wrinkle monograph
Primary Sources: 2026-03-12
Biotin
Common Name(s): Vitamin b7,vitamin h,d-biotin
CAS Number: 58-85-5
DESCRIPTION
What It Does: Supports keratin production for stronger hair and nails.
Why It's Used: Hair and nail keratin infrastructure support; widely marketed despite evidence being primarily oral supplementation-based.
How It Works: Coenzyme for carboxylase enzymes essential for fatty acid synthesis and amino acid metabolism relevant to hair follicle function.
Typically Found In: Hair growth shampoos,nail treatments,multivitamin products
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin b7
Secondary Functions: Hair growth support,nail strengthening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ0.5%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Evidence for topical biotin efficacy in hair growth is limited โ most clinical evidence comes from oral supplementation in biotin-deficient individuals.
Last Verified: Cosing database,cir safety assessment,patel et al. (2017) skin appendage disorders
Primary Sources: 2026-03-12
Biotin
Common Name(s): Vitamin b7,vitamin h,d-biotin
CAS Number: 58-85-5
DESCRIPTION
What It Does: Supports keratin production for stronger hair and nails.
Why It's Used: Hair and nail keratin infrastructure support; widely marketed despite evidence being primarily oral supplementation-based.
How It Works: Coenzyme for carboxylase enzymes essential for fatty acid synthesis and amino acid metabolism relevant to hair follicle function.
Typically Found In: Hair growth shampoos,nail treatments,multivitamin products
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin b7
Secondary Functions: Hair growth support,nail strengthening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ0.5%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Evidence for topical biotin efficacy in hair growth is limited โ most clinical evidence comes from oral supplementation in biotin-deficient individuals.
Last Verified: Cosing database,cir safety assessment,patel et al. (2017) skin appendage disorders
Primary Sources: 2026-03-12
Caffeine
Common Name(s): Caffeine,methylxanthine anti-cellulite,antioxidant vasoactive
CAS Number: N/a
DESCRIPTION
What It Does: Stimulates lipolysis in adipocytes by inhibiting phosphodiesterase (preventing camp breakdown), reduces eye puffiness through vasoconstriction of periorbital capillaries, and provides antioxidant dna repair stimulation for photoprotective benefit.
Why It's Used: The only cosmetic active with a well-defined mechanism for anti-cellulite claims โ phosphodiesterase inhibition elevating adipocyte camp is the documented biochemical pathway, providing mechanism-based efficacy substantiation superior to most slimming actives.
How It Works: Caffeine inhibits phosphodiesterase (pde3, pde4) preventing camp hydrolysis โ elevated camp activates protein kinase a โ phosphorylates hormone-sensitive lipase โ lipolysis of triglycerides in adipocytes. for eye puffiness: caffeine's adenosine receptor antagonism reduces prostaglandin-mediated capillary dilation in periorbital tissue, reducing fluid accumulation.
Typically Found In: Anti-cellulite,eye creams,antioxidant products
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ3%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Caffeine has one of the highest sc penetration rates of any cosmetic active (logp -0.07, mw 194 da) โ the combination of small size and moderate logp providing excellent aqueous solubility with sufficient sc lipid partitioning for effective transdermal delivery to adipose tissue.
Last Verified: Cosing database,caffeine pde inhibitor anti-cellulite lipolysis review
Primary Sources: 2026-03-12
Personalized Usage Instructions
How to Use
Step 1
After cleansing with Re:GRO Anti-Thinning Shampoo & Conditioner, towel dry
Step 2
Apply the serum directly to your scalp in lines front to back, or side to side, about a quarter apart, squeezing as you go
Step 3
Massage in with fingertips, spreading it to ensure all areas of the scalp are covered
Step 4
No need to rinse
Step 5
Use at least 4 times per week for 12 weeks for best results
Medical Chemicals
Protein/Moisture
- Protein/Moisture balance
pH Level
- Acidic
Porosity Taget
- Normal Porosity
Customized for Your Profile
Scalp Condtions
Sensitive Scalp, pH Balanced, Oil Control, Dry Scalp
Climate Suitability
Humid, Dry, Hard Water, Soft Water, UV Protection, Pollution Shield, Winter, Summer
Clinical Claims
5% Capixyl - Clinically shown to spark new growth and strengthen thinning hair. *Source: Capixyl Lucas Meyer Cosmetics by Clariant.
Frequency
After cleansing with Re:GRO Anti-Thinning Shampoo & Conditioner, towel dry. Apply the serum directly to your scalp in lines front to back, or side to side, about a quarter apart, squeezing as you go. Massage in with fingertips, spreading it to ensure all areas of the scalp are covered. No need to rinse. Use at least 4 times per week for 12 weeks for best results.
Product Information
Clean Ingredients
Cruelty-Free
Vegan
Sustainable Packaging
Give Back