Cold Plasma Plus+ Daily Defense Moisturizer Broad Spectrum SPF 35

Perricone MD

Cold Plasma Plus+ Daily Defense Moisturizer Broad Spectrum SPF 35

Cold Plasma Plus+ Daily Defense Moisturizer Broad Spectrum SPF 35

Perricone MD

cold-plasma-plus-daily-defense-moisturizer-broad-spectrum-spf-35

Moisturize, Suncare

9643618009381

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

Add to Routine
Compare with Similar

Compatibility Score

0%

Microbiome
Ingredients
Biological
Environment
Lifestyle

How It Fits Into Your Skincare Routine

Login to see compatibility score and learn how this works with your skin.

Highlights

WHAT IS IT?

Moisturizer with SPF protection

FEATURES

Corrects photodamage, reduces discoloration and redness, prevents visible photoaging, protects against UVA and UVB rays

BEST FOR

All skin types

CHECKS

Fragrance-free

Who Is It For?

Adults Both Women And Men

What Does It Help With?

Fine Lines Wrinkles Uneven Texture Uneven Skin Tone Dullness Redness Enlarged Pores

Budget

Premium

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Massage onto cleansed face and neck using a gentle upward motion in the morning. For best results, apply after your favorite Perricone MD serum, serum concentrate or facial cream.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Perricone MD Says

Product Description:

A weightless, multi-tasking powerhouse that corrects, prevents and protects against sun damage while promoting the most visible signs of healthy, youthful-looking skin. Vitamin C Ester and copper tripeptide work together with our liquid crystal delivery system to visibly reduce fine lines, wrinkles, uneven texture and tone, dullness, redness and enlarged pores. Leaves skin feeling hydrated, smooth and protected.

About the Brand:

Founded by Dr. Nicholas Perricone, Perricone MD is a pioneer in the science of aging. This brand takes a holistic approach to skincare, combining cutting-edge ingredients with a focus on nutrition and lifestyle. Experience transformative results with products that address not just the signs of aging, but its underlying causes.

Ingredients Overview

Ingredients List

Water/Aqua/Eau, Glycerin, Dimethicone, Isononyl Isononanoate, Ethylhexyl Methoxycrylene, C12-15 Alkyl Benzoate, Niacinamide, Silica, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Phenoxyethanol, Stearic Acid, Isohexadecane, Tetrahexyldecyl Ascorbate, Polysilicone-11, Butylene Glycol, Aluminum Hydroxide, Phosphatidylcholine, Bisabolol, Polyhydroxystearic Acid, Isopropyl Titanium Triisostearate, Polysorbate 60, Xanthan Gum, Sorbitan Isostearate, Copper Tripeptide-1, Citric Acid, Mica, Carbomer, Potassium Sorbate, Polysorbate 20, Sodium Hyaluronate, Sodium Lactate, Helianthus Annuus (Sunflower) Seed Oil, Sodium Benzoate, Acetyl Hexapeptide-8, Tocopherol, Rosmarinus Officinalis (Rosemary) Leaf Extract, Ascorbyl Palmitate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Triethoxycaprylylsilane, CI 77891 (Titanium Dioxide), CI 42090 (Blue 1 Lake)

Key Ingredients

Vitamin C Ester, Copper Tripeptide, Mineral-Based Sunscreen

Ingredients Details

C12-15 Alkyl Benzoate

Common Name(s): C12-15 alkyl benzoate,cosmetic active,functional ingredient

CAS Number: N/a

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class โ€” physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

C12-15 alkyl benzoate has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,c12-15 alkyl benzoate technical literature

Primary Sources: 2026-03-12

Dimethicone

Common Name(s): Pdms,polydimethylsiloxane,silicone fluid

CAS Number: 9006-65-9

DESCRIPTION

What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.

Why It's Used: The benchmark cosmetic silicone โ€“ sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.

How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.

Typically Found In: Moisturizers,foundations,primers,sunscreens โ€“ nearly universal

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ polydimethylsiloxane

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“30%

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetic

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 1/5 โ€“ low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material โ€“ explaining why even small amounts transform product feel.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Ethylhexyl Methoxycrylene

Common Name(s): Ethylhexyl methoxycrylene,cosmetic active,functional ingredient

CAS Number: N/a

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class โ€” physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ethylhexyl methoxycrylene has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,ethylhexyl methoxycrylene technical literature

Primary Sources: 2026-03-12

Glycerin

Common Name(s): Glycerol,glycerine,1,2,3-propanetriol

CAS Number: 56-81-5

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“30% (typical: 3โ€“10%)

SOURCING & ETHICS

Vegan Status: Yes โ€“ plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes โ€“ when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12