
Highlights
WHAT IS IT?
A water-based serum
FEATURES
Clinically proven to reduce surface oil, congestion, and visible redness
BEST FOR
Combination, oily, and blemish-prone skin
CHECKS
Free of parabens, talc, phthalates, synthetic fragrances, fillers, GMO ingredients
Who Is It For?
Adults (18+) Both Men And WomenWhat Does It Help With?
Reduces Surface Oil Congestion And Visible RednessBudget
PremiumHow To Use
Which routine should it be used in?
Instructions:
Key Information
What ZO Skin Health Says
Product Description:
A water-based serum engineered with ZO® sebum-targeting science, clinically proven to reduce surface oil, congestion + visible redness for a continually clear + balanced complexion. This foundational staple is formulated for a range of skin types, especially combination, oily + blemish-prone skin. Fragrance- and alcohol-free.
About the Brand:
Ingredients Overview
Ingredients List
Aqua/Water/Eau, Propanediol, Glycerin, Salicylic Acid, Sodium Polyacrylate, Butylene Glycol, Eugenia Uniflora Leaf Extract, Laminaria Digitata Extract, Rosa Canina Fruit Extract, Syringa Vulgaris (Lilac) Extract, Opuntia Ficus-Indica Stem Extract, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Meristem Cell Culture, Lecithin, Galactoarabinan, Schizophyllan, Maltodextrin, Caprylyl Glycol, Phytic Acid, Trisodium Ethylenediamine Disuccinate, Inulin Lauryl Carbamate, Acacia Senegal Gum, Xanthan Gum, Mannitol, Sodium Citrate, Hydroxyacetophenone, Trehalose, Sodium Bisulfite, Ergothioneine, Phenoxyethanol, Chlorphenesin, Benzyl Alcohol, Potassium Sorbate, Sodium Benzoate.
Key Ingredients
Z-SEB³™ (Eugenia uniflora leaf extract, Syringa vulgaris extract, Rosa Canina extract), Water-Soluble Salicylic Acid, ZO-RRS2®, ZPOLY™
Ingredients Details
Butylene Glycol
Common Name(s): 1,3-butanediol,bg,1,3-butylene glycol
CAS Number: 107-88-0
DESCRIPTION
What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.
Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.
How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.
Typically Found In: Toners,essences,serums,k-beauty formulas
TECHNICAL DETAILS
Primary Category: Functional ingredient – glycol humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%–10%
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Eugenia Uniflora Leaf Extract
Common Name(s): Eugenia uniflora leaf extract,inci ingredient,cosmetic active
CAS Number: N/a
DESCRIPTION
What It Does: Provides documented cosmetic activity from eugenia uniflora leaf extract.
Why It's Used: Eugenia uniflora leaf extract delivers formulation value through its specific biological activity and established safety and efficacy.
How It Works: Source: eugenia uniflora leaf extract. mechanism: documented in cosmetic literature. safety: cosing-reviewed. standard cosmetic use concentrations.
Typically Found In: Skin care formulations,active products
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–5%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Eugenia uniflora leaf extract provides cosmetic activity through its characteristic mechanism. at standard concentrations it delivers documented biological activity with an established safety profile from cosmetic science literature and regulatory review.
Last Verified: Cosing database,eugenia uniflora leaf extract technical literature
Primary Sources: 2026-03-12
Glycerin
Common Name(s): Glycerol,glycerine,1,2,3-propanetriol
CAS Number: 56-81-5
DESCRIPTION
What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.
Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.
How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.
Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners
TECHNICAL DETAILS
Primary Category: Humectant
Secondary Functions: Skin barrier support,emollient,solvent
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%–30% (typical: 3–10%)
SOURCING & ETHICS
Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic
Halal Status: Yes – when plant-derived or synthetic; verify source with supplier
Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).
Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas
Avoid Combining With: No known incompatibilities at standard concentrations
SCIENTIFIC NOTE
Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder
Primary Sources: 2026-03-12
Laminaria Digitata Extract
Common Name(s): Laminaria digitata extract,botanical extract,phytochemical active
CAS Number: N/a
DESCRIPTION
What It Does: Provides antioxidant protection from reactive oxygen species, reduces inflammatory cytokine production in skin, and conditions skin through the plant's phytochemical complex.
Why It's Used: Natural origin narrative, traditional use heritage, and multi-functional phytochemical profile supporting concurrent skin care claims from one ingredient.
How It Works: Polyphenols, terpenoids, and alkaloids scavenge ros via h• donation, inhibit nf-kb or cox-2 inflammatory pathways, and interact with skin surface proteins for conditioning.
Typically Found In: Botanical skin care,natural products
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Plant secondary metabolites evolved as photoprotectants and antimicrobials — mechanisms directly applicable to cosmetic antioxidant and anti-inflammatory activity in human skin.
Last Verified: Cosing database,laminaria digitata extract botanical review
Primary Sources: 2026-03-12