Complexion Clarifying Serum

ZO Skin Health

Complexion Clarifying Serum

Complexion Clarifying Serum

ZO Skin Health

complexion-clarifying-serum

Serum

9706802381093

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

Add to Routine
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Compatibility Score

0%

Microbiome
Ingredients
Biological
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Lifestyle

How It Fits Into Your Skincare Routine

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Highlights

WHAT IS IT?

A water-based serum

FEATURES

Clinically proven to reduce surface oil, congestion, and visible redness

BEST FOR

Combination, oily, and blemish-prone skin

CHECKS

Free of parabens, talc, phthalates, synthetic fragrances, fillers, GMO ingredients

Who Is It For?

Adults (18+) Both Men And Women

What Does It Help With?

Reduces Surface Oil Congestion And Visible Redness

Budget

Premium

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Apply to clean, dry skin morning and night.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What ZO Skin Health Says

Product Description:

A water-based serum engineered with ZO® sebum-targeting science, clinically proven to reduce surface oil, congestion + visible redness for a continually clear + balanced complexion. This foundational staple is formulated for a range of skin types, especially combination, oily + blemish-prone skin. Fragrance- and alcohol-free.

About the Brand:

Founded by renowned dermatologist Dr. Zein Obagi, ZO Skin Health offers a comprehensive approach to creating and maintaining healthy skin. With its cutting-edge formulations and skin health science, this brand provides powerful solutions for all skin types and concerns. Discover a new level of skin transformation with ZO Skin Health's medical-grade products.

Ingredients Overview

Ingredients List

Aqua/Water/Eau, Propanediol, Glycerin, Salicylic Acid, Sodium Polyacrylate, Butylene Glycol, Eugenia Uniflora Leaf Extract, Laminaria Digitata Extract, Rosa Canina Fruit Extract, Syringa Vulgaris (Lilac) Extract, Opuntia Ficus-Indica Stem Extract, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Meristem Cell Culture, Lecithin, Galactoarabinan, Schizophyllan, Maltodextrin, Caprylyl Glycol, Phytic Acid, Trisodium Ethylenediamine Disuccinate, Inulin Lauryl Carbamate, Acacia Senegal Gum, Xanthan Gum, Mannitol, Sodium Citrate, Hydroxyacetophenone, Trehalose, Sodium Bisulfite, Ergothioneine, Phenoxyethanol, Chlorphenesin, Benzyl Alcohol, Potassium Sorbate, Sodium Benzoate.

Key Ingredients

Z-SEB³™ (Eugenia uniflora leaf extract, Syringa vulgaris extract, Rosa Canina extract), Water-Soluble Salicylic Acid, ZO-RRS2®, ZPOLY™

Ingredients Details

Butylene Glycol

Common Name(s): 1,3-butanediol,bg,1,3-butylene glycol

CAS Number: 107-88-0

DESCRIPTION

What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.

Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.

How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.

Typically Found In: Toners,essences,serums,k-beauty formulas

TECHNICAL DETAILS

Primary Category: Functional ingredient – glycol humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Eugenia Uniflora Leaf Extract

Common Name(s): Eugenia uniflora leaf extract,inci ingredient,cosmetic active

CAS Number: N/a

DESCRIPTION

What It Does: Provides documented cosmetic activity from eugenia uniflora leaf extract.

Why It's Used: Eugenia uniflora leaf extract delivers formulation value through its specific biological activity and established safety and efficacy.

How It Works: Source: eugenia uniflora leaf extract. mechanism: documented in cosmetic literature. safety: cosing-reviewed. standard cosmetic use concentrations.

Typically Found In: Skin care formulations,active products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Eugenia uniflora leaf extract provides cosmetic activity through its characteristic mechanism. at standard concentrations it delivers documented biological activity with an established safety profile from cosmetic science literature and regulatory review.

Last Verified: Cosing database,eugenia uniflora leaf extract technical literature

Primary Sources: 2026-03-12

Glycerin

Common Name(s): Glycerol,glycerine,1,2,3-propanetriol

CAS Number: 56-81-5

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

Laminaria Digitata Extract

Common Name(s): Laminaria digitata extract,botanical extract,phytochemical active

CAS Number: N/a

DESCRIPTION

What It Does: Provides antioxidant protection from reactive oxygen species, reduces inflammatory cytokine production in skin, and conditions skin through the plant's phytochemical complex.

Why It's Used: Natural origin narrative, traditional use heritage, and multi-functional phytochemical profile supporting concurrent skin care claims from one ingredient.

How It Works: Polyphenols, terpenoids, and alkaloids scavenge ros via h• donation, inhibit nf-kb or cox-2 inflammatory pathways, and interact with skin surface proteins for conditioning.

Typically Found In: Botanical skin care,natural products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Plant secondary metabolites evolved as photoprotectants and antimicrobials — mechanisms directly applicable to cosmetic antioxidant and anti-inflammatory activity in human skin.

Last Verified: Cosing database,laminaria digitata extract botanical review

Primary Sources: 2026-03-12