
Highlights
WHAT IS IT?
Night moisturizer with 17 ingredients
FEATURES
Locks in skin's hydration overnight, provides 24 hour hydration, improves skin's resilience and hydration
BEST FOR
All skin types including sensitive
CHECKS
Does not contain oils, fragrances, parabens
Who Is It For?
Adults Both Women And MenWhat Does It Help With?
Dryness Irritation Roughness Tightness Weakened Skin BarrierBudget
Mid-rangeHow To Use
Which routine should it be used in?
Instructions:
Key Information
What Cetaphil Says
Product Description:
Lightweight, oil-free lotion rehydrates skin, boosting moisture reserves for lasting hydration overnight
About the Brand:
Ingredients Overview
Ingredients List
Water, Dicaprylyl Carbonate, Hydroxyethyl Urea, Cyclopentasiloxane, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Hydrolyzed Hyaluronic Acid, Sodium Hydroxide, Homarine HCI, Sodium PCA, Cetyl Alcohol, Caprylyl Glycol, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Erythritol
Key Ingredients
Hyaluronic Acid
Ingredients Details
Cyclopentasiloxane
Common Name(s): Cyclopentasiloxane,cyclic volatile silicone,dry-touch carrier solvent
CAS Number: N/a
DESCRIPTION
What It Does: Provides a dry, weightless application vehicle that evaporates cleanly leaving actives and non-volatile silicones deposited on skin โ eliminating the residual heaviness of conventional liquid carrier solvents.
Why It's Used: Cyclosiloxanes are the unique volatile silicone solvents that dissolve non-volatile silicones (dimethicone, cyclomethicone), organic uv filters, and lipophilic actives, providing the sensory-superior dry-touch application experience in premium formulations.
How It Works: Cyclosiloxane vapour pressure (d5 cyclopentasiloxane ~0.3 mmhg at 25ยฐc) provides clean evaporation at body temperature. the cyclic ring structure provides lower boiling point than equivalent linear dimethicone, enabling faster evaporation while the ring conformation maintains the silicone's low surface energy for smooth application.
Typically Found In: Primers,antiperspirants,sunscreens
TECHNICAL DETAILS
Primary Category: Functional ingredient โ emollient
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ50%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 1/5 โ low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Cyclopentasiloxane (d5) and cyclohexasiloxane (d6) are under eu regulatory review for potential environmental persistence (pbt assessment) โ formulators should monitor eu regulation 2018/35 implementation for restrictions in wash-off products.
Last Verified: Cosing database,eu cyclosiloxane regulatory review
Primary Sources: 2026-03-12
Dicaprylyl Carbonate
Common Name(s): Dicaprylyl carbonate,cosmetic active,functional ingredient
CAS Number: N/a
DESCRIPTION
What It Does: Delivers characteristic cosmetic function at recommended use concentration.
Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.
How It Works: Works through the mechanism of its molecular class โ physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.
Typically Found In: Skin care formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Dicaprylyl carbonate has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.
Last Verified: Cosing database,dicaprylyl carbonate technical literature
Primary Sources: 2026-03-12
Glycerin
Common Name(s): Glycerol,glycerine,1,2,3-propanetriol
CAS Number: 56-81-5
DESCRIPTION
What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.
Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.
How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.
Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners
TECHNICAL DETAILS
Primary Category: Humectant
Secondary Functions: Skin barrier support,emollient,solvent
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ30% (typical: 3โ10%)
SOURCING & ETHICS
Vegan Status: Yes โ plant-derived (coconut, soy, palm) or synthetic
Halal Status: Yes โ when plant-derived or synthetic; verify source with supplier
Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; non-irritating at all standard concentrations
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).
Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas
Avoid Combining With: No known incompatibilities at standard concentrations
SCIENTIFIC NOTE
Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder
Primary Sources: 2026-03-12
Glyceryl Stearate
Common Name(s): Glycerol monostearate,gms,glycerin monostearate
CAS Number: 31566-31-1
DESCRIPTION
What It Does: Provides o/w emulsification with emolliency and skin feel improvement from a natural glycerol ester.
Why It's Used: Standard cosmetic monoglyceride emulsifier โ widely used for o/w cream formation with clean, natural-origin credentials and good sensory profile.
How It Works: Monoglyceride structure (one fatty acid + glycerol) provides amphiphilic hlb ~3-4 for o/w emulsification when combined with higher hlb co-emulsifiers. forms alpha-gel lamellar structure with water for emulsion stabilization. direct skin conditioning via fatty acid film.
Typically Found In: Creams,lotions,moisturizers โ standard in o/w emulsions
TECHNICAL DETAILS
Primary Category: Functional ingredient โ monoglyceride emulsifier
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ10%
SOURCING & ETHICS
Vegan Status: Yes โ from vegetable glycerol and stearic acid
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 1/5 โ low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Glyceryl stearate's alpha-gel lamellar phase formation (distinguishable by x-ray crystallography from beta crystalline phase) provides superior emulsion stability compared to its beta crystalline form. the alpha-gel phase creates a viscoelastic network that resists droplet coalescence โ the fundamental mechanism behind gms's long use as a reliable primary emulsifier.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12