Dramatically Different Moisturizing Lotion+™

DESCRIPTION

What It Does: Provides antioxidant protection, anti-inflammatory activity, and skin conditioning from polyphenols, terpenoids, and phytochemicals in the extract.

Why It's Used: Natural plant extracts provide multi-functional phytochemical profiles supporting concurrent skin care claims from one ingredient with authentic botanical heritage.

How It Works: Polyphenols scavenge ros via h• donation; terpenoids inhibit nf-kb or cox inflammatory pathways; vitamins and minerals provide cofactor skin nutrition.

Typically Found In: Botanical skin care,natural products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–30%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Conditional

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Plant secondary metabolites evolved for uv photoprotection and pathogen defence — mechanisms directly applicable to cosmetic antioxidant and anti-inflammatory activity in human skin.

Last Verified: Cosing database,cucumis sativus (cucumber) fruit ex botanical review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides o/w emulsification with emolliency and skin feel improvement from a natural glycerol ester.

Why It's Used: Standard cosmetic monoglyceride emulsifier – widely used for o/w cream formation with clean, natural-origin credentials and good sensory profile.

How It Works: Monoglyceride structure (one fatty acid + glycerol) provides amphiphilic hlb ~3-4 for o/w emulsification when combined with higher hlb co-emulsifiers. forms alpha-gel lamellar structure with water for emulsion stabilization. direct skin conditioning via fatty acid film.

Typically Found In: Creams,lotions,moisturizers – standard in o/w emulsions

TECHNICAL DETAILS

Primary Category: Functional ingredient – monoglyceride emulsifier

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – from vegetable glycerol and stearic acid

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Glyceryl stearate's alpha-gel lamellar phase formation (distinguishable by x-ray crystallography from beta crystalline phase) provides superior emulsion stability compared to its beta crystalline form. the alpha-gel phase creates a viscoelastic network that resists droplet coalescence – the fundamental mechanism behind gms's long use as a reliable primary emulsifier.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Lanolin alcohol has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,lanolin alcohol technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the highest level of skin occlusion and wound healing protection of any cosmetic ingredient.

Why It's Used: The most effective skin barrier protection ingredient available – fda-approved otc skin protectant with unparalleled occlusive moisturization and wound healing evidence.

How It Works: Semi-solid blend of long-chain hydrocarbons creates an extremely cohesive, impermeable occlusive film. physically prevents bacterial and irritant ingress while completely preventing tewl. does not absorb into skin. promotes moist wound healing environment by maintaining wound surface hydration.

Typically Found In: Intensive moisturizers,wound healing ointments,lip balms,baby products,eczema treatments

TECHNICAL DETAILS

Primary Category: Functional ingredient – petroleum ointment base / gold-standard occlusive

Secondary Functions: Maximum occlusion,wound healing,otc skin protectant

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–100%

SOURCING & ETHICS

Vegan Status: Yes – petroleum-derived

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic (clinical evidence)

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Fda category i grase otc skin protectant. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Petrolatum's wound healing mechanism (moist wound healing) was first systematically studied by george winter (1962) and demonstrated that wounds heal 2× faster under occlusion than air-exposed. all subsequent wound dressings and occlusive skin treatments are based on this fundamental finding, with petrolatum remaining the most effective occlusive agent 60 years later.

Last Verified: Cosing database,fda otc skin protectant monograph,winter (1962) moist wound healing study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Nourishes and softens skin through its balanced fatty acid profile, while antioxidant compounds protect against oxidative skin damage.

Why It's Used: Plant oils provide physiologically compatible lipid structures that integrate into the skin barrier and deliver fat-soluble antioxidants directly to skin cells.

How It Works: Fatty acids integrate into stratum corneum lipid lamellae, reinforcing the lipid barrier. antioxidants (tocopherols, carotenoids, polyphenols) neutralize ros through electron donation or singlet oxygen quenching.

Typically Found In: Face oils,serums,moisturizers,hair treatments,body oils

TECHNICAL DETAILS

Primary Category: Plant oils

Secondary Functions: Emollient,antioxidant

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5–30%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Cold-pressed or solvent-extracted plant oil; no animal components.

SKIN COMPATIBILITY

Irritancy Rating: 1899-12-31 00:00:00 -0800

Comedogenicity Rating: 1900-01-01 00:00:00 -0800

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Vitamin e,ceramides,other plant oils,squalane

Avoid Combining With: Strong oxidizers (accelerate rancidity)

SCIENTIFIC NOTE

Vegetable oils are triglyceride matrices where the fatty acid composition determines skin compatibility, barrier function, and comedogenicity. oleic acid-rich oils (>60%) soften barrier lipids and enhance penetration; linoleic acid-rich oils reinforce ceramide-poor stratum corneum; saturated fatty acid-rich oils provide occlusion without skin penetration.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; aocs plant oil composition databases; fatty acid pharmacology reviews

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides fatty acid thickening and emolliency with soap-forming emulsification when neutralized.

Why It's Used: Classic cosmetic fatty acid used in virtually all cream and lotion formulations for thickening, emolliency, and opacification.

How It Works: Forms metal soaps (sodium stearate, potassium stearate) on reaction with alkalis for self-emulsification. crystallizes in lamellar networks for thickening. waxy solid provides opacification. low-viscosity melt above 69°c for easy processing.

Typically Found In: Creams,soaps,cleansers,emulsions – foundational ingredient

TECHNICAL DETAILS

Primary Category: Functional ingredient – c18 saturated fatty acid

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–15%

SOURCING & ETHICS

Vegan Status: Yes – from vegetable (palm, shea, soy stearin)

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 2/5 – low

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Stearic acid's dual role as both an emulsifier precursor (when saponified to sodium stearate soap) and an emollient (as unmodified fatty acid) is unique among cosmetic fatty acids. in soap-based cleansers, stearic acid is intentionally partially saponified to create a balanced system: excess stearic acid provides skin-conditioning emolliency while the sodium stearate provides surfactancy – the chemical basis for 'superfatted' soaps.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Triethanolamine has an established safety profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,triethanolamine technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: At 2–10%: provides deep humectancy, softens sc, and improves other active penetration. at 10–40%: keratolytically dissolves corneocyte protein bonds for intensive exfoliation of hyperkeratotic skin (calluses, eczema plaques, psoriasis).

Why It's Used: Urea combines two otherwise separate ingredient classes (humectant and keratolytic) in one molecule, with formulator-controlled function through concentration selection — uniquely versatile for multiple skin condition applications.

How It Works: Urea's carbonyl and amine groups form h-bonds with water (humectancy) and with corneocyte keratin (penetration). at high concentrations, urea disrupts keratin hydrogen bonds (chaotropic activity) solubilising the sc protein matrix — concentration determines whether humectant or keratolytic effect predominates.

Typically Found In: Eczema,hyperkeratosis,callus care,moisturising

TECHNICAL DETAILS

Primary Category: Functional ingredient – humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 2%–40%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Urea is the most concentrated natural nmf component — healthy sc contains 28 mg/g urea versus 2 mg/g in xerotic (dry) skin. topical urea application directly replenishes the physiological nmf deficit that drives dry skin conditions.

Last Verified: Cosing database,urea nmf dual function humectant keratolytic review

Primary Sources: 2026-03-12