
Highlights
WHAT IS IT?
Antioxidant serum with EUK-134 0.1%
FEATURES
Self-regenerating molecule that mimics effects of two powerful antioxidants found naturally in skin
BEST FOR
normal
CHECKS
Water-free, alcohol-free, oil-free, silicone-free, gluten-free
Who Is It For?
All Ages And GendersWhat Does It Help With?
Antioxidant Support Skin Brightening Protection From Environmental StressorsBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What The Ordinary Says
Product Description:
An antioxidant formula that brightens your skin
About the Brand:
Ingredients Overview
Ingredients List
Propanediol, Ethylbisiminomethylguaiacol-Manganese-Chloride
Key Ingredients
EUK-134, Propanediol
Ingredients Details
Ethylbisiminomethylguaiacol Manganese Chloride
Common Name(s): Ethylbisiminomethylguaiacol manganese chloride
DESCRIPTION
What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.
Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.
How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix โ enzymes, receptors, structural proteins, or signaling molecules โ triggering beneficial biological responses.
Typically Found In: Serums,treatments,moisturizers,specialty products
TECHNICAL DETAILS
Primary Category: Specialty actives
Secondary Functions: Skin-conditioning,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Specialty active ingredient; check individual sourcing for vegan status.
SKIN COMPATIBILITY
Irritancy Rating: 1
Comedogenicity Rating: 0
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides
Avoid Combining With: Incompatible with oxidizing agents; check ph stability
SCIENTIFIC NOTE
Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-ฮณ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Propanediol
Common Name(s): 1,3-propanediol,zemea,bio-propanediol
CAS Number: 504-63-2
DESCRIPTION
What It Does: Provides humectant and solvent functionality from sustainable corn-based fermentation.
Why It's Used: Bio-based propylene glycol alternative from renewable corn โ propanediol provides equivalent functionality to propylene glycol with sustainable renewable feedstock and superior skin feel.
How It Works: Two oh groups provide humectant water binding. excellent solvent for fragrances, actives, and preservatives. mild antimicrobial from diol structure for preservative system boosting. renew corn fermentation origin (dupont zemea process). better skin feel than propylene glycol โ less sticky.
Typically Found In: Virtually all cosmetic categories as pg alternative
TECHNICAL DETAILS
Primary Category: Functional ingredient โ humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ20%
SOURCING & ETHICS
Vegan Status: Yes โ from corn sugar fermentation
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Propanediol's dupont tate & lyle bio products 'zemea' process ferments corn sugar to 1,3-propanediol using engineered e. coli โ one of the first commercially viable bio-fermentation routes to a cosmetic diol previously made only from petroleum. the renewable route produces chemically identical 1,3-propanediol while reducing carbon footprint by approximately 40% vs petrochemical synthesis.
Last Verified: Cosing database,dupont tate & lyle zemea technical data,cir safety assessment
Primary Sources: 2026-03-12