Eye Peptides

DESCRIPTION

What It Does: Alcohol denat. dissolves oil-soluble and water-soluble cosmetic actives, provides rapid antimicrobial activity at concentrations above 60–70% by denaturing microbial proteins, delivers a refreshing cooling sensation through evaporative cooling on skin, and temporarily enhances the penetration of topical actives by transiently disrupting the stratum corneum lipid bilayer organisation.

Why It's Used: Formulators choose alcohol denat. for its irreplaceable combination of solvent power, antimicrobial activity, and penetration-enhancing properties. no other cosmetic solvent simultaneously provides the cooling sensory experience of alcohol (from evaporative cooling at the skin surface), the immediate antimicrobial activity required for sanitisers (from protein denaturation above 60%), and the transient sc lipid disruption that improves active ingredient delivery (essential in actives-rich toners and essences). for denatured alcohol specifically, denaturing agents (typically 5% isopropanol or bitrex) prevent consumption without affecting cosmetic function.

How It Works: Alcohol denat. works through multiple mechanisms depending on concentration: (1) solvent action — alcohol's hydroxyl group provides hydrogen bonding with water while the short alkyl chain provides interaction with organic solutes, enabling dissolution of both hydrophilic and moderately lipophilic cosmetic actives in a single solvent; (2) antimicrobial — above 60% concentration, ethanol denatures microbial proteins by disrupting non-covalent bonds maintaining protein secondary and tertiary structure — the alcohol molecules intercalate between protein chains, disrupting the hydrophobic interactions and hydrogen bonds that maintain enzyme active site geometry. this non-specific protein denaturation is immediately bactericidal and virucidal with no resistance mechanism possible; (3) sc penetration enhancement — at lower concentrations (5–30%), ethanol transiently fluidises the sc lipid bilayer by intercalating between the ordered lipid lamellae, disrupting the crystal packing and increasing lipid bilayer fluidity. this transient fluidisation increases the diffusion coefficient of co-applied actives through the sc for up to 30 minutes post-application; (4) astringency — alcohol's protein precipitating action at the skin surface contracts superficial proteins, temporarily tightening pores and reducing oiliness.

Typically Found In: Toners,hand sanitisers,actives serums

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 5%–95%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ethanol concentration-dependent antimicrobial efficacy: below 40% — minimal bactericidal effect (insufficient protein denaturation); 40–60% — bacteriostatic, not bactericidal; 60–70% — peak bactericidal efficacy against both enveloped and non-enveloped viruses and vegetative bacteria (optimal water content maintains protein hydration required for denaturation to proceed); 80–90% — remains effective but slightly reduced from decreased water activity; 95–100% — reduced efficacy (insufficient water for protein denaturation). the 70% 'sweet spot' for sanitisers reflects this concentration-efficacy peak, not a formulation convenience.

Last Verified: Cosing database,alcohol denat. ethanol solvent antimicrobial review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides dual fragrance and preservative activity as an aromatic alcohol.

Why It's Used: Multi-function ingredient serving as both fragrance component and preservative – reduces formulation complexity by providing both functions in one ingredient.

How It Works: Phenylcarbinol provides antimicrobial activity via membrane disruption (effective vs gram-positive bacteria and moulds). solvent for fragrances and difficult-to-dissolve actives. mild oxidative conversion to benzaldehyde provides sweet almond-like fragrance.

Typically Found In: Fragrances,preserved cosmetics,solvent systems

TECHNICAL DETAILS

Primary Category: Fragrance component / preservative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–1% (fragrance); up to 1% as preservative

SOURCING & ETHICS

Vegan Status: Yes – from toluene, or jasmine absolute

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. also listed as approved preservative (annex v, max 1%). dual regulatory status (fragrance + preservative) depending on function and concentration.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Benzyl alcohol's dual regulatory status (fragrance allergen and approved preservative) creates a formulation paradox: it must be listed as a fragrance allergen if present >0.001% (leave-on) regardless of whether it was added for fragrance or preservation. this regulatory dual identity means a preservative added for antimicrobial function triggers the same allergen declaration requirement as a fragrance added for scent.

Last Verified: Cosing database,ifra standards,eu preservative annex v

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.

Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.

How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.

Typically Found In: Toners,essences,serums,k-beauty formulas

TECHNICAL DETAILS

Primary Category: Functional ingredient – glycol humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

C12-15 alkyl benzoate has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,c12-15 alkyl benzoate technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Strengthens skin barrier and reduces inflammation in sensitive, atopic, and compromised skin.

Why It's Used: Part of comprehensive ceramide barrier repair complexes; important for formulations targeting sensitive and atopic dermatitis-prone skin.

How It Works: Dihydrosphingosine backbone provides slightly different lamellar packing geometry than sphingosine-based ceramides, filling structural positions within the lamellar body that other ceramides cannot occupy.

Typically Found In: Sensitive skin moisturizers,eczema care,barrier repair serums

TECHNICAL DETAILS

Primary Category: Active ingredient – ceramide / barrier lipid

Secondary Functions: Anti-inflammatory,barrier support

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–1%

SOURCING & ETHICS

Vegan Status: Conditional – synthetic or plant-derived; verify

Halal Status: Conditional – synthetic is halal; animal-derived verify

Source Notes: Synthetic production or phytoceramide analog from plant sources.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Endogenous molecule; excellent tolerability.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Exceptional safety profile. natural skin component. ewg score: 1.

Works Well With: Other ceramides,cholesterol,free fatty acids,hyaluronic acid,niacinamide

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Ceramide ng and np together represent the majority of stratum corneum ceramide content. their complementary lamellar body positioning means both are required for complete barrier restoration – formulations with both show clinically superior barrier repair vs single ceramide products.

Last Verified: Cosing database,elias ceramide structure review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides vegan rice protein conditioning for hair strengthening and film formation.

Why It's Used: Leading vegan plant protein for hair conditioning formulations as an alternative to animal-derived hydrolyzed proteins.

How It Works: High glutelin and prolamin peptide content provides film-forming adsorption to hair surface. amino acid conditioning for hair and skin. lower cysteine than keratin hydrolysate but excellent vegan alternative. good substantivity via hydrogen bonding.

Typically Found In: Vegan hair conditioners,plant-based hair treatments

TECHNICAL DETAILS

Primary Category: Active ingredient – plant protein

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–10%

SOURCING & ETHICS

Vegan Status: Yes – from oryza sativa (rice) protein

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Rice protein's amino acid profile (high in glutamic acid and leucine) provides different conditioning character than wheat (glutamine-dominant) or silk (glycine/alanine-dominant) proteins. rice protein hydrolysate forms slightly less cohesive films than wheat protein but deposits more evenly across the hair fiber due to lower molecular weight distribution.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Steareth-20 has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,steareth-20 technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Softens and conditions skin with a light, non-greasy feel.

Why It's Used: Used for its solid waxy triglyceride; high-mp from three c22 chains; structured emolliency; long-wear emollient properties; suitable for lightweight skin care where non-greasy texture is key.

How It Works: Ester of glycerol (branched or specialty alcohol) with behenic acid (c22, triglyceride); branching reduces crystallinity and greasiness; provides smooth, dry-oil skin feel.

Typically Found In: Lightweight moisturizers,sunscreens,skin serums,body lotions

TECHNICAL DETAILS

Primary Category: Functional ingredient – emollient

Secondary Functions: Skin conditioning,texture modification,spreading agent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–10%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Glycerol and behenic acid (c22, triglyceride); plant or synthetic origin.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low

Sensitivity Concerns: Generally well tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile. ewg score: 1.

Works Well With: Other emollients,silicones,natural oils,humectants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Tribehenin: glycerol esterified with three behenic acid (c22) chains; very high melting point waxy triglyceride; provides structured texture and substantive emolliency in color cosmetics and premium skin care.

Last Verified: Cosing database,inci dictionary

Primary Sources: 2026-03-28

DESCRIPTION

What It Does: Provides pseudoplastic thickening and emulsion/suspension stabilization across broad ph and salt conditions.

Why It's Used: The most versatile cosmetic thickener – pseudoplastic behavior (shear-thinning) provides ideal pump dispensing while maintaining in-use viscosity, stable across ph 2-12 and in high-salt formulations.

How It Works: Helix-coil conformational transitions provide pseudoplastic (shear-thinning) rheology. electrostatic repulsion between negatively charged chains provides thickening without cross-linking. stable across ph 2-12 and at nacl concentrations up to saturation.

Typically Found In: Virtually all aqueous cosmetic products requiring viscosity control

TECHNICAL DETAILS

Primary Category: Functional ingredient – microbial polysaccharide thickener

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–2%

SOURCING & ETHICS

Vegan Status: Yes – microbial fermentation (xanthomonas campestris)

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Xanthan gum's pseudoplastic behavior arises from helix alignment under shear (reducing viscosity) that recovers to random coil entanglement at rest (restoring viscosity). the 100-1000× viscosity reduction during pumping vs at rest makes xanthan the ideal pump-dispensing thickener – providing both easy dispensing and in-use viscosity that neither purely viscous nor elastic thickeners can achieve simultaneously.

Last Verified: Cosing database,cir safety assessment,fda gras

Primary Sources: 2026-03-12