Fixderma Nigrifix Cream For Acanthosis Nigricans For Dark Neck, Ankles, Knuckles & Elbows

Fixderma India Pvt Ltd.

Fixderma Nigrifix Cream For Acanthosis Nigricans For Dark Neck, Ankles, Knuckles & Elbows

Fixderma Nigrifix Cream For Acanthosis Nigricans For Dark Neck, Ankles, Knuckles & Elbows

Fixderma India Pvt Ltd.

fixderma-nigrifix-cream-for-acanthosis-nigricans-for-dark-neck-ankles-knuckles-elbows

Moisturize

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Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

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Compatibility Score

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Highlights

WHAT IS IT?

Cream product with multiple active ingredients (exact count not provided)

FEATURES

Lightweight, non-greasy formula; Absorbs well; Nourishes the skin; Improves skin texture; Reduces pigmentation; Moisturizes skin; Suitable for dark, rough, thickened skin

BEST FOR

sensitive

CHECKS

Does not contain parabens, not greasy

Who Is It For?

Adults (general Adult Age Range No Gender Specified)

What Does It Help With?

Acanthosis Nigricans Dark Skin Patches Rough And Thickened Skin Pigmentation Moisturization

Budget

Affordable (under $30)

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Usage instructions not explicitly provided in the content

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Fixderma India Pvt Ltd. Says

Product Description:

Fixderma Nigrifix Cream is a great solution for managing dark, rough, and thickened skin, especially in areas like the neck, underarms, and knees. The formula is lightweight, non-greasy, and absorbs well into the skin. With consistent use, it helps improve skin texture, reduce pigmentation, and keep the skin moisturized, preventing dryness or irritation.

About the Brand:

Fixderma stands at the intersection of dermatological science and practical skincare solutions, addressing complex skin concerns with medical precision. Founded by dermatologists who understood the gap between clinical treatments and daily skincare, this brand has become synonymous with results-driven formulations. Their research team collaborates directly with practicing dermatologists to identify real-world skin challenges and develop targeted solutions. Each product is backed by clinical studies and formulated with pharmaceutical-grade actives at therapeutic concentrations.

Ingredients Overview

Ingredients List

Retinol (0.1%), Lactic Acid (10%), Urea, Surfactants, Emollients, Preservatives

Key Ingredients

Ingredients Details

Preservatives

Common Name(s): Preservatives,functional category descriptor,cosmetic ingredient class

CAS Number: N/a

DESCRIPTION

What It Does: Represents the functional class benefits of the 'preservatives' category; specific activity depends on the individual ingredient.

Why It's Used: Used in consumer-facing ingredient communication and formulation descriptions when referring to ingredient classes rather than specific inci names.

How It Works: Mechanism varies by specific ingredient within the category โ€” the category designation indicates shared primary function.

Typically Found In: Consumer communication

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Varies

SOURCING & ETHICS

Vegan Status: Varies

Halal Status: Varies

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Preservatives' encompasses multiple specific inci ingredients โ€” refer to individual ingredient entries for specific mechanism, concentration, and safety data.

Last Verified: Cosing database,functional category descriptor

Primary Sources: 2026-03-12

Urea

Common Name(s): Urea,nmf component keratolytic,dual humectant+exfoliant

CAS Number: N/a

DESCRIPTION

What It Does: At 2โ€“10%: provides deep humectancy, softens sc, and improves other active penetration. at 10โ€“40%: keratolytically dissolves corneocyte protein bonds for intensive exfoliation of hyperkeratotic skin (calluses, eczema plaques, psoriasis).

Why It's Used: Urea combines two otherwise separate ingredient classes (humectant and keratolytic) in one molecule, with formulator-controlled function through concentration selection โ€” uniquely versatile for multiple skin condition applications.

How It Works: Urea's carbonyl and amine groups form h-bonds with water (humectancy) and with corneocyte keratin (penetration). at high concentrations, urea disrupts keratin hydrogen bonds (chaotropic activity) solubilising the sc protein matrix โ€” concentration determines whether humectant or keratolytic effect predominates.

Typically Found In: Eczema,hyperkeratosis,callus care,moisturising

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 2%โ€“40%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Urea is the most concentrated natural nmf component โ€” healthy sc contains 28 mg/g urea versus 2 mg/g in xerotic (dry) skin. topical urea application directly replenishes the physiological nmf deficit that drives dry skin conditions.

Last Verified: Cosing database,urea nmf dual function humectant keratolytic review

Primary Sources: 2026-03-12