Growth Factor Eye Serum

ZO Skin Health

Growth Factor Eye Serum

Growth Factor Eye Serum

ZO Skin Health

growth-factor-eye-serum

Eyecare

9706803036453

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

Add to Routine
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Compatibility Score

0%

Microbiome
Ingredients
Biological
Environment
Lifestyle

How It Fits Into Your Skincare Routine

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Highlights

WHAT IS IT?

Eye serum

FEATURES

Cooling applicator, clinically proven technology

BEST FOR

All skin types

CHECKS

Free of parabens, talc, phthalates, synthetic fragrances, fillers, GMO ingredients

Who Is It For?

Adults Both Men And Women

What Does It Help With?

Expression Lines Creasing Hollowness Tired Eyes

Budget

Premium

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Apply to clean, dry skin. Draw small, gentle circles into the eye orbital area in the AM/PM or as needed.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What ZO Skin Health Says

Product Description:

Powered by clinically proven ZO® Growth Factor technology, Growth Factor Eye Serum is designed to help improve the appearance of expression lines, creasing + hollowness while plumping + encouraging healthy skin for a visibly revived look. The cooling applicator soothes the skin + re-invigorates the look of tired eyes.

About the Brand:

Founded by renowned dermatologist Dr. Zein Obagi, ZO Skin Health offers a comprehensive approach to creating and maintaining healthy skin. With its cutting-edge formulations and skin health science, this brand provides powerful solutions for all skin types and concerns. Discover a new level of skin transformation with ZO Skin Health's medical-grade products.

Ingredients Overview

Ingredients List

Aqua/Water/Eau, Dimethicone, Dipropylene Glycol, Butylene Glycol, Glycerin, Bellis Perennis (Daisy) Flower Extract, Dimethicone/PEG-10/15 Crosspolymer, PEG/PPG-18/18 Dimethicone, Lupinus Albus Seed Oil, Triticum Vulgare (Wheat) Germ Oil, PEG-35 Castor Oil, Hieracium Pilosella Extract, Scutellaria Baicalensis Root Extract, Cordyceps Militaris Mycelium Extract, Glycyrrhiza Uralensis (Licorice) Root Extract, Angelica Polymorpha Sinesis Root Extract, Buddleja Davidii Meristem Cell Culture, Lactobacillus/Panax Ginseng Root Ferment Filtrate, Sodium Chloride, Dimethicone Crosspolymer, Lactobacillus Ferment, Phospholipids, Sodium Citrate, Sodium Tocopheryl Phosphate, Hydrolyzed Sericin, Cera Alba/Beeswax/Cire d'abeille, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Acetylated Hyaluronate, Panthenyl Triacetate, Acetyl Tyrosine, Ethyl Linoleate, 1,2-Hexanediol, Pentylene Glycol, Proline, Citric Acid, Hydrolyzed Vegetable Protein, Oleyl Alcohol, Trisodium Citrate Dihydrate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Silica, Silica Silylate, Beta-Glucan, Tocopherol, Disodium Acetyl Glucosamine Phosphate, Adenosine Triphosphate, Caprylyl Glycol, Hexylene Glycol, PEG-12 Glyceryl Laurate, Acetyl Tetrapeptide-5, Xanthan Gum, Disodium EDTA, PVP, Sodium Benzoate, Sodium Dehydroacetate, Phenoxyethanol, Potassium Sorbate.

Key Ingredients

ZO® Growth Factor Technology, Neuropeptide, Sodium acetylated hyaluronate

Ingredients Details

Butylene Glycol

Common Name(s): 1,3-butanediol,bg,1,3-butylene glycol

CAS Number: 107-88-0

DESCRIPTION

What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.

Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.

How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.

Typically Found In: Toners,essences,serums,k-beauty formulas

TECHNICAL DETAILS

Primary Category: Functional ingredient – glycol humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Dimethicone

Common Name(s): Pdms,polydimethylsiloxane,silicone fluid

CAS Number: 9006-65-9

DESCRIPTION

What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.

Why It's Used: The benchmark cosmetic silicone – sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.

How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.

Typically Found In: Moisturizers,foundations,primers,sunscreens – nearly universal

TECHNICAL DETAILS

Primary Category: Functional ingredient – polydimethylsiloxane

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–30%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material – explaining why even small amounts transform product feel.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Dimethicone/peg-10/15 Crosspolymer

Common Name(s): Dimethicone/peg-10/15 crosspolymer

DESCRIPTION

What It Does: Reduces surface tension at oil-water interfaces, enabling effective cleansing, emulsification, and formulation stability.

Why It's Used: Surface-active agents are essential for emulsification, cleansing, and stabilization of cosmetic formulations containing both aqueous and lipid phases.

How It Works: The amphiphilic molecular structure positions the hydrophilic head in water and the lipophilic tail in oils, creating micelles that solubilize sebum, dirt, and oil-soluble impurities for rinsing in cleansers or stable emulsions in leave-on products.

Typically Found In: Cleansers,shampoos,body washes,foaming treatments

TECHNICAL DETAILS

Primary Category: Surfactants

Secondary Functions: Emulsifying,cleansing

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5–30%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic or semi-synthetic surfactant; no animal components.

SKIN COMPATIBILITY

Irritancy Rating: 2

Comedogenicity Rating: 0

Sensitivity Concerns: May cause irritation or stinging in sensitive or barrier-compromised skin at high concentrations; patch test recommended.

Safe for Sensitive Skin: Conditional

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. mildly irritating to some individuals at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Other surfactants,thickeners,conditioning agents

Avoid Combining With: High concentrations in sensitive skin formulations

SCIENTIFIC NOTE

Surfactant critical micelle concentration (cmc) determines the threshold for emulsification: above the cmc, amphiphilic molecules self-assemble into micelles with hydrophobic cores that solubilize oils. hlb (hydrophile-lipophile balance) value predicts surfactant function: hlb 3–6 for w/o emulsifiers, 8–18 for o/w emulsifiers, >15 for solubilizers.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15

Dipropylene Glycol

Common Name(s): Dipropylene glycol,glycol co-solvent,humectant formulation aid

CAS Number: N/a

DESCRIPTION

What It Does: Provides humectant, co-solvent, and fragrance fixative in cosmetic formulations, improving active ingredient dissolution and product texture while delivering mild skin conditioning.

Why It's Used: Glycol solvents are essential for dissolving actives with limited water or oil solubility — the intermediate polarity of glycol ethers provides access to the wider solubility parameter space between pure water and oil phases.

How It Works: Hydroxyl and ether groups provide h-bonding for water miscibility; the organic chain provides compatibility with lipophilic actives. medium-chain glycols (c3–c6) provide the optimal balance of water compatibility, lipophilic active dissolution, and skin-compatible humectancy.

Typically Found In: Skin care formulations,co-solvent systems

TECHNICAL DETAILS

Primary Category: Functional ingredient – humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Glycol ether co-solvents enhance sc penetration of co-applied actives by increasing their thermodynamic activity in the sc lipid phase — high thermodynamic activity (near saturation) drives diffusion by concentration gradient even when absolute concentration is low.

Last Verified: Cosing database,dipropylene glycol glycol solvent review

Primary Sources: 2026-03-12