
Highlights
WHAT IS IT?
Advanced Anti Ageing Face Serum with 5 key ingredients
FEATURES
Minimizes fine lines & wrinkles, Repairs signs of aging rapidly, Boosts collagen to firm skin, Hydrates & soothes skin, 30% more effective than Retinol Serum, 100% Vegan, Paraben-free, SLS-free, Alcohol-free, Zero Plastic Footprint
BEST FOR
sensitive
CHECKS
Parabens,SLS,Alcohol
Who Is It For?
All Genders No Specific Age Range MentionedWhat Does It Help With?
Anti-ageing Fine Lines Wrinkles Skin Firming Hydration SoothingBudget
Mid-range ($30-$75)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Hyphen Says
Product Description:
Get ready to reset the clock on your skin’s health with the power of Hyphen 0.1% Retinal Reset Serum Pro - Advanced. Add this serum to your regime to unlock transformative effects as the serum helps in minimizing fine lines & wrinkles, repairing signs of aging rapidly, boosting collagen to firm skin & hydrating & soothing your skin. This is made effective with a combination of ingredients like Retinal- 0.1%, Antioxidants Blend 7%, Plant stem cells, Cica Extracts 10%, Squalane 2%. This anti-ageing serum is 100% Vegan, PETA Certified, Paraben-free, SLS-free, and Alcohol-free, with Zero Plastic Footprint. Additionally, all Hyphen products uphold sustainable values, ensuring a positive impact on both your skin and the planet.
About the Brand:
Ingredients Overview
Ingredients List
Retinal-0.1%,Antioxidants-Blend-7%,Plant-stem-cells,Cica-Extracts-10%,Squalane-2%
Key Ingredients
Retinal,Antioxidants Blend,Plant stem cells,Cica Extracts,Squalane
Ingredients Details
Retinal
Common Name(s): Retinoid active,rar nuclear receptor,anti-aging gold standard
CAS Number: N/a
DESCRIPTION
What It Does: Stimulates collagen i and iii synthesis, accelerates epidermal renewal, inhibits mmp-1 collagenase, normalises pigmentation, and reverses photoaging signs including wrinkles, laxity, and texture.
Why It's Used: The most clinically validated anti-aging mechanism in dermatology with 40+ years of peer-reviewed evidence — retinoids are the benchmark against which all anti-aging actives are compared.
How It Works: Retinol and esters are enzymatically converted in skin: retinol → retinaldehyde (alcohol dehydrogenase) → all-trans retinoic acid (retinaldehyde dehydrogenase). retinoic acid binds rar-α/β/γ → rare promoter binding → col1a1, timp-1 upregulation; mmp-1 and il-6 downregulation through ap-1 pathway interference.
Typically Found In: Anti-aging serums,night creams
TECHNICAL DETAILS
Primary Category: Active ingredient – vitamin a derivative
Secondary Functions: Collagen booster,antioxidant
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.025%–2% (check local limits)
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic or plant-derived. requires opaque, airless packaging.
SKIN COMPATIBILITY
Irritancy Rating: 2/5 – low to moderate
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Introduce slowly; retinization expected at higher potencies.
Safe for Sensitive Skin: Use with caution – avoid during pregnancy
SAFETY & COMPATIBILITY
Safety Profile: Safe at cosmetic concentrations. use spf. avoid during pregnancy. ewg score: 2.
Works Well With: Niacinamide,ceramides,hyaluronic acid,spf,tocopherol
Avoid Combining With: Pregnancy; extended uv without spf; benzoyl peroxide
SCIENTIFIC NOTE
Different retinoid potency ladder: retinyl palmitate < retinol < retinaldehyde < retinyl retinoate ≈ hpr < all-trans retinoic acid. corresponding irritation follows the same order — formulators select the potency/tolerance balance for their target consumer.
Last Verified: Cosing database,retinoid anti-aging rar clinical evidence review
Primary Sources: 2026-03-12
Squalane
Common Name(s): Perhydrosqualene,2,6,10,15,19,23-hexamethyltetracosane
CAS Number: 0111-01-03
DESCRIPTION
What It Does: Provides endogenous-skin-identical emolliency with exceptional stability and skin compatibility.
Why It's Used: The most skin-compatible emollient – chemically identical to human sebum squalene component with outstanding tolerability across all skin types.
How It Works: Fully saturated hydrocarbon with zero oxidation sites provides exceptional stability unlike squalene's 6 double bonds. integrates into stratum corneum lipid bilayers with near-perfect biocompatibility. provides antioxidant protection to formulation via radical quenching.
Typically Found In: Facial oils,serums,non-comedogenic moisturizers,luxury body care
TECHNICAL DETAILS
Primary Category: Functional ingredient – emollient
Secondary Functions: Maximum biocompatibility,antioxidant stabilizer,non-comedogenic
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%–100%
SOURCING & ETHICS
Vegan Status: Conditional – plant-derived (sugarcane, olive) preferred; shark liver-derived being phased out
Halal Status: Yes – plant-derived
Source Notes: Sustainable plant-derived squalane from sugarcane fermentation (amyris) or olive oil fractionation is preferred over shark liver-derived. chemically identical regardless of source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Squalene constitutes approximately 12-15% of human sebum – the highest proportion of any skin lipid. topical squalane (stable, hydrogenated form) replenishes this abundant endogenous skin lipid. the complete absence of oxidizable double bonds (unlike squalene's 6 double bonds) eliminates the pro-oxidant concerns of natural squalene oxidation.
Last Verified: Cosing database,huang et al. squalane review,cir safety assessment
Primary Sources: 2026-03-12